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Complement Factor B Protein (CFB) (AA 26-764) (His tag)

CFB 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096421
发货至: 中国
  • 抗原 See all Complement Factor B (CFB) 蛋白
    Complement Factor B (CFB)
    蛋白类型
    Recombinant
    产品特性
    AA 26-764
    宿主
    • 12
    • 6
    • 4
    • 1
    资源
    • 14
    • 6
    • 2
    • 1
    人细胞
    标记
    This Complement Factor B protein is labelled with His tag.
    原理
    Recombinant Human Complement Factor B/CFB (C-6His)
    序列
    TPWSLAWPQG SCSLEGVEIK GGSFRLLQEG QALEYVCPSG FYPYPVQTRT CRSTGSWSTL KTQDQKTVRK AECRAIHCPR PHDFENGEYW PRSPYYNVSD EISFHCYDGY TLRGSANRTC QVNGRWSGQT AICDNGAGYC SNPGIPIGTR KVGSQYRLED SVTYHCSRGL TLRGSQRRTC QEGGSWSGTE PSCQDSFMYD TPQEVAEAFL SSLTETIEGV DAEDGHGPGE QQKRKIVLDP SGSMNIYLVL DGSDSIGASN FTGAKKCLVN LIEKVASYGV KPRYGLVTYA TYPKIWVKVS EADSSNADWV TKQLNEINYE DHKLKSGTNT KKALQAVYSM MSWPDDVPPE GWNRTRHVII LMTDGLHNMG GDPITVIDEI RDLLYIGKDR KNPREDYLDV YVFGVGPLVN QVNINALASK KDNEQHVFKV KDMENLEDVF YQMIDESQSL SLCGMVWEHR KGTDYHKQPW QAKISVIRPS KGHESCMGAV VSEYFVLTAA HCFTVDDKEH SIKVSVGGEK RDLEIEVVLF HPNYNINGKK EAGIPEFYDY DVALIKLKNK LKYGQTIRPI CLPCTEGTTR ALRLPPTTTC QQQKEELLPA QDIKALFVSE EEKKLTRKEV YIKNGDKKGS CERDAQYAPG YDKVKDISEV VTPRFLCTGG VSPYADPNTC RGDSGGPLIV HKRSRFIQVG VISWGVVDVC KNQKRQKQVP AHARDFHINL FQVLPWLKEK LQDEDLGFLV DHHHHHH
    产品特性
    Recombinant Human Complement Factor B/CFB is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Thr26-Leu764) of Human CFB fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CFB 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Complement Factor B (CFB)
    别名
    complement-factor-b (CFB 产品)
    别名
    AHUS4 Protein, BF Protein, BFD Protein, CFAB Protein, FB Protein, FBI12 Protein, GBG Protein, H2-Bf Protein, PBF2 Protein, bf Protein, Bf-1 Protein, Brre-Bf Protein, zgc:114032 Protein, Bf Protein, Sp152 Protein, bfb-A Protein, Bf B Protein, LOC397725 Protein, bf/c2 Protein, CFB Protein, AI195813 Protein, AI255840 Protein, B Protein, C2 Protein, Fb Protein, Da1-24 Protein, complement factor B Protein, complement factor B S homeolog Protein, complement factor B L homeolog Protein, CFB Protein, cfb Protein, bf Protein, cfb.S Protein, cfb.L Protein, bf/c2 Protein, LOC100555981 Protein, Cfb Protein
    Sub Type
    Fusionprotein
    背景
    Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
    Alternative Names: Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD
    分子量
    84.07 kDa
    UniProt
    P00751
    途径
    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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