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Chitotriosidase 1 Protein (AA 22-466) (His tag)

CHIT1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096386
发货至: 中国
  • 抗原 See all Chitotriosidase 1 (CHIT1) 蛋白
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    蛋白类型
    Recombinant
    产品特性
    AA 22-466
    宿主
    • 7
    • 2
    • 1
    资源
    • 3
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This Chitotriosidase 1 protein is labelled with His tag.
    原理
    Recombinant Human Chitotriosidase-1/CHIT1 (C-6His)
    序列
    AKLVCYFTNW AQYRQGEARF LPKDLDPSLC THLIYAFAGM TNHQLSTTEW NDETLYQEFN GLKKMNPKLK TLLAIGGWNF STQKFTDMVA TANNRQTFVN SAIRFLRKYS FDGLDLDWEY PGSQGSPAVD KERFTTLVQD LANAFQQEAQ TSGKERLLLS AAVPAGQTYV DAGYEVDKIA QNLDFVNLMA YDFHGSWEKV TGHNSPLYKR QEESGAAASL NVDAAVQQWL QKGTPASKLI LGMPTYGRSF TLASSSDTRV GAPATGSGTP GPFTKEGGML AYYEVCSWKG ATKQRIQDQK VPYIFRDNQW VGFDDVESFK TKVSYLKQKG LGGAMVWALD LDDFAGFSCN QGRYPLIQTL RQELSLPYLP SGTPELEVPK PGQPSEPEHG PSPGQDTFCQ GKADGLYPNP RERSSFYSCA GGRLFQQSCP TGLVFSNSCK CCTWNVDHHH HHH
    产品特性
    Recombinant Human Chitotriosidase-1/CHIT1 produced by transfected human cells is a secreted protein with sequence (Ala22-Asn466) of Human CHIT1 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CHIT1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    别名
    chitotriosidase (CHIT1 产品)
    别名
    CHI3 Protein, CHIT Protein, CHITD Protein, CHIT1 Protein, chio Protein, 2300002L19Rik Protein, chitinase 1 Protein, chitinase 1 (chitotriosidase) Protein, CHIT1 Protein, chit1 Protein, Chit1 Protein
    Sub Type
    Fusionprotein
    背景
    Chitotriosidase-1 (CHIT1) is a glycoprotein that belongs to the Glycosyl Hydrolase 18 family and Chitinase class II subfamily. It is secreted by cultured macrophages and serves to degrade chitin, chitotriose and chitobiose. CHIT1 may participate in the defense against nematodes and other pathogens. It is highly expressed in the plasma of patients with Gaucher's disease type I, which can be used as diagnostic aid and to evaluate the success of treatment that brings levels back to normal. The amino acid sequence of human CHIT1 is 99%, 76%, 75% and 55% identical to that of chimpanzee, rat, mouse and fruit fly, respectively.
    Alternative Names: Chitotriosidase-1, Chitinase-1, CHIT1
    分子量
    50.43 kDa
    UniProt
    Q13231
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