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Cathepsin S Protein (CTSS) (AA 17-331) (His tag)

CTSS 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096245
发货至: 中国
  • 抗原 See all Cathepsin S (CTSS) 蛋白
    Cathepsin S (CTSS)
    蛋白类型
    Recombinant
    产品特性
    AA 17-331
    宿主
    • 8
    • 6
    • 3
    • 3
    • 1
    • 1
    资源
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This Cathepsin S protein is labelled with His tag.
    原理
    Recombinant Human Cathepsin S/CTSS (C-6His)
    序列
    QLHKDPTLDH HWHLWKKTYG KQYKEKNEEA VRRLIWEKNL KFVMLHNLEH SMGMHSYDLG MNHLGDMTSE EVMSLMSSLR VPSQWQRNIT YKSNPNWILP DSVDWREKGC VTEVKYQGSC GACWAFSAVG ALEAQLKLKT GKLVSLSAQN LVDCSTEKYG NKGCNGGFMT TAFQYIIDNK GIDSDASYPY KAMDQKCQYD SKYRAATCSK YTELPYGRED VLKEAVANKG PVSVGVDARH PSFFLYRSGV YYEPSCTQNV NHGVLVVGYG DLNGKEYWLV KNSWGHNFGE EGYIRMARNK GNHCGIASFP SYPEIVDHHH HHH
    产品特性

    Recombinant Human Cathepsin S/CTSS (C-6His)

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CTSS 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 10 % Glycerol, pH 5.5.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Cathepsin S (CTSS)
    别名
    Cathepsin S (CTSS 产品)
    别名
    ctss-a Protein, MGC69026 Protein, ctss-b Protein, MGC80097 Protein, ctss.1 Protein, CTSS Protein, ctss Protein, cats Protein, cathepsin S Protein, cathepsin S L homeolog Protein, cathepsin S S homeolog Protein, Cathepsin S Protein, CTSS Protein, Ctss Protein, ctss.L Protein, ctss.S Protein, ctss Protein, cats Protein
    背景
    Recombinant Human Cathepsin S is produced with our mammalian expression system in human cells. The target protein is expressed with the full length sequence of Human CTSS fused with a polyhistidine tag at the C-terminus.
    Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A β from amyloidogenic fragments of β APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS).
    分子量
    36.89 kDa
    UniProt
    P25774
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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