GLB1 Protein (AA 24-677) (His tag)
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- 抗原 See all GLB1 蛋白
- GLB1 (Galactosidase, beta 1 (GLB1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-677
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宿主
- 人
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资源
- 人细胞
- 标记
- This GLB1 protein is labelled with His tag.
- 原理
- Recombinant Human β-Galactosidase/GLB1 (C-6His)
- 序列
- LRNATQRMFE IDYSRDSFLK DGQPFRYISG SIHYSRVPRF YWKDRLLKMK MAGLNAIQTY VPWNFHEPWP GQYQFSEDHD VEYFLRLAHE LGLLVILRPG PYICAEWEMG GLPAWLLEKE SILLRSSDPD YLAAVDKWLG VLLPKMKPLL YQNGGPVITV QVENEYGSYF ACDFDYLRFL QKRFRHHLGD DVVLFTTDGA HKTFLKCGAL QGLYTTVDFG TGSNITDAFL SQRKCEPKGP LINSEFYTGW LDHWGQPHST IKTEAVASSL YDILARGASV NLYMFIGGTN FAYWNGANSP YAAQPTSYDY DAPLSEAGDL TEKYFALRNI IQKFEKVPEG PIPPSTPKFA YGKVTLEKLK TVGAALDILC PSGPIKSLYP LTFIQVKQHY GFVLYRTTLP QDCSNPAPLS SPLNGVHDRA YVAVDGIPQG VLERNNVITL NITGKAGATL DLLVENMGRV NYGAYINDFK GLVSNLTLSS NILTDWTIFP LDTEDAVRSH LGGWGHRDSG HHDEAWAHNS SNYTLPAFYM GNFSIPSGIP DLPQDTFIQF PGWTKGQVWI NGFNLGRYWP ARGPQLTLFV PQHILMTSAP NTITVLELEW APCSSDDPEL CAVTFVDRPV IGSSVTYDHP SKPVEKRLMP PPPQKNKDSW LDHVVDHHHH HH
- 产品特性
- Recombinant Human beta-Galactosidase/GLB1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (L24-V677) of Human GLB1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GLB1 蛋白
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Galactosidase, beta 1 (GLB1) protein (Fc Tag)
GLB1 宿主: E. coli 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.
Galactosidase, beta 1 (GLB1) (AA 578-677) protein (GST tag)GLB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Galactosidase, beta 1 (GLB1) (AA 1-677) protein (GST tag)GLB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- GLB1 (Galactosidase, beta 1 (GLB1))
- 别名
- glb1 (GLB1 产品)
- 别名
- EBP Protein, ELNR1 Protein, MPS4B Protein, DER Protein, XR Protein, 0610038K04Rik Protein, 1810027P18Rik Protein, glb Protein, CG9092 Protein, Dmel\\CG9092 Protein, beta-GAL Protein, beta-Gal-1 Protein, beta-gal Protein, gal Protein, lacZ-1 Protein, AW125515 Protein, Bge Protein, Bgl Protein, Bgl-e Protein, Bgl-s Protein, Bgl-t Protein, Bgs Protein, Bgt Protein, C130097A14Rik Protein, BGAL Protein, zgc:110823 Protein, ECK0341 Protein, JW0335 Protein, GLB Protein, galactosidase beta 1 Protein, dicarbonyl and L-xylulose reductase Protein, dicarbonyl L-xylulose reductase Protein, beta-D-galactosidase Protein, beta-galactosidase Protein, beta galactosidase Protein, galactosidase, beta 1 Protein, beta-galactosidase-like Protein, GLB1 Protein, DCXR Protein, Dcxr Protein, lacZ Protein, SSP_RS00525 Protein, lacH Protein, ECL_03691 Protein, Gal Protein, Glb1 Protein, glb1 Protein, VV2_1327 Protein, LOC100056371 Protein
- Sub Type
- Fusionprotein
- 背景
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Beta Galactosidase is a lysosomal beta Galactosidase that hydrolyzes the terminal beta Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature beta Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of beta Galactosidase results a catalytically inactive beta Galactosidase that plays an important role in vascular development. Defects of beta-galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 100 mutations have been identified for beta Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
Alternative Names: Beta-Galactosidase, Acid Beta-Galactosidase, Lactase, Elastin Receptor 1, GLB1, ELNR1 - 分子量
- 74.63 kDa
- UniProt
- P16278
- 途径
- Glycosaminoglycan Metabolic Process
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