beta Arrestin 1 Protein (AA 1-418) (His tag)
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- 抗原 See all beta Arrestin 1 (ARRB1) 蛋白
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-418
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This beta Arrestin 1 protein is labelled with His tag.
- 原理
- Recombinant Human β-Arrestin 1/ARRB1 (C-6His)
- 序列
- MGDKGTRVFK KASPNGKLTV YLGKRDFVDH IDLVDPVDGV VLVDPEYLKE RRVYVTLTCA FRYGREDLDV LGLTFRKDLF VANVQSFPPA PEDKKPLTRL QERLIKKLGE HAYPFTFEIP PNLPCSVTLQ PGPEDTGKAC GVDYEVKAFC AENLEEKIHK RNSVRLVIRK VQYAPERPGP QPTAETTRQF LMSDKPLHLE ASLDKEIYYH GEPISVNVHV TNNTNKTVKK IKISVRQYAD ICLFNTAQYK CPVAMEEADD TVAPSSTFCK VYTLTPFLAN NREKRGLALD GKLKHEDTNL ASSTLLREGA NREILGIIVS YKVKVKLVVS RGGLLGDLAS SDVAVELPFT LMHPKPKEEP PHREVPENET PVDTNLIELD TNDDDIVFED FARQRLKGMK DDKEEEEDGT GSPQLNNRLE HHHHHH
- 产品特性
- Recombinant Human beta-Arrestin 1/ARRB1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Arg418) of Human ARRB1.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ARRB1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- 别名
- beta-arrestin-1 (ARRB1 产品)
- 别名
- arrb1 Protein, MGC83787 Protein, arb1 Protein, arr1 Protein, barr1 Protein, betaarr1 Protein, 1200006I17Rik Protein, AW208571 Protein, G430100A01Rik Protein, ARB1 Protein, ARR1 Protein, BARRES Protein, arrestin beta 1 Protein, arrestin, beta 1 Protein, arrestin beta 1 L homeolog Protein, beta-arrestin 1 Protein, putative beta-arrestin 1 Protein, ARRB1 Protein, arrb1 Protein, arrb1.L Protein, CpipJ_CPIJ016988 Protein, CpipJ_CPIJ017114 Protein, Smp_122900 Protein, Smp_126080 Protein, Smp_176980 Protein, Smp_152290 Protein, Arrb1 Protein
- 背景
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Beta-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.
Alternative Names: Beta-Arrestin-1, Arrestin Beta-1, ARRB1, ARR1 - 分子量
- 48.13 kDa
- UniProt
- P49407
- 途径
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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