beta Arrestin 1 Protein (His tag)
-
- 抗原 See all beta Arrestin 1 (ARRB1) 蛋白
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This beta Arrestin 1 protein is labelled with His tag.
- 原理
- Recombinant Human β-Arrestin 1/ARRB1 Protein (His Tag)
- 序列
- Met 1-Arg418
- 产品特性
- Recombinant Human beta-Arrestin 1 is produced by our E.coli expression system and the target gene encoding Met1-Arg418 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ARRB1 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- 别名
- beta-Arrestin 1/ARRB1 (ARRB1 产品)
- 别名
- arrb1 Protein, MGC83787 Protein, arb1 Protein, arr1 Protein, barr1 Protein, betaarr1 Protein, 1200006I17Rik Protein, AW208571 Protein, G430100A01Rik Protein, ARB1 Protein, ARR1 Protein, BARRES Protein, arrestin beta 1 Protein, arrestin, beta 1 Protein, arrestin beta 1 L homeolog Protein, beta-arrestin 1 Protein, putative beta-arrestin 1 Protein, ARRB1 Protein, arrb1 Protein, arrb1.L Protein, CpipJ_CPIJ016988 Protein, CpipJ_CPIJ017114 Protein, Smp_122900 Protein, Smp_126080 Protein, Smp_176980 Protein, Smp_152290 Protein, Arrb1 Protein
- 背景
-
Background: β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.
Synonym: Beta-Arrestin-1, Arrestin Beta-1, ARRB1, ARR1
- 分子量
- 48.1 kDa
- UniProt
- P49407
- 途径
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
-