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beta Arrestin 1 Protein (His tag)

ARRB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319213
发货至: 中国
  • 抗原 See all beta Arrestin 1 (ARRB1) 蛋白
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 4
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This beta Arrestin 1 protein is labelled with His tag.
    原理
    Recombinant Human β-Arrestin 1/ARRB1 Protein (His Tag)
    序列
    Met 1-Arg418
    产品特性
    Recombinant Human beta-Arrestin 1 is produced by our E.coli expression system and the target gene encoding Met1-Arg418 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ARRB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    别名
    beta-Arrestin 1/ARRB1 (ARRB1 产品)
    别名
    arrb1 Protein, MGC83787 Protein, arb1 Protein, arr1 Protein, barr1 Protein, betaarr1 Protein, 1200006I17Rik Protein, AW208571 Protein, G430100A01Rik Protein, ARB1 Protein, ARR1 Protein, BARRES Protein, arrestin beta 1 Protein, arrestin, beta 1 Protein, arrestin beta 1 L homeolog Protein, beta-arrestin 1 Protein, putative beta-arrestin 1 Protein, ARRB1 Protein, arrb1 Protein, arrb1.L Protein, CpipJ_CPIJ016988 Protein, CpipJ_CPIJ017114 Protein, Smp_122900 Protein, Smp_126080 Protein, Smp_176980 Protein, Smp_152290 Protein, Arrb1 Protein
    背景

    Background: β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.

    Synonym: Beta-Arrestin-1, Arrestin Beta-1, ARRB1, ARR1

    分子量
    48.1 kDa
    UniProt
    P49407
    途径
    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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