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ACVR2A Protein (AA 20-134) (His tag)

ACVR2A 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1095960
发货至: 中国
  • 抗原 See all ACVR2A 蛋白
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    蛋白类型
    Recombinant
    产品特性
    AA 20-134
    宿主
    • 11
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
    • 6
    • 5
    • 2
    • 1
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    人细胞
    标记
    This ACVR2A protein is labelled with His tag.
    原理
    Recombinant Human Activin Receptor 2A/Activin RIIA/ACVR2A (C-6His)
    序列
    AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPVDHHH HHH
    产品特性
    Recombinant Human Activin Receptor Type-2A/ACVR2A is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala20-Pro134) of Human ACVR2A fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ACVR2A 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    Abstract
    ACVR2A 产品
    别名
    ACVR2 Protein, ACVR2A Protein, XSTK9 Protein, actrii Protein, acvr2 Protein, ACTRII Protein, Acvr2 Protein, rActR-II Protein, actr2a Protein, acvr2a Protein, wu:fa02e10 Protein, ActrIIa Protein, TactrII Protein, activin A receptor type 2A Protein, activin A receptor type 2A L homeolog Protein, activin A receptor type 2Aa Protein, activin receptor IIA Protein, ACVR2A Protein, acvr2a Protein, Acvr2a Protein, acvr2a.L Protein, acvr2aa Protein
    Sub Type
    Fusionprotein
    背景
    Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
    Alternative Names: Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2
    分子量
    14.35 kDa
    UniProt
    P27037
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