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ACVR2A Protein (AA 20-134) (Fc Tag,His tag)

ACVR2A 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1880618
发货至: 中国
  • 抗原 See all ACVR2A 蛋白
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    蛋白类型
    Recombinant
    产品特性
    AA 20-134
    宿主
    • 11
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    资源
    • 6
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    人细胞
    标记
    This ACVR2A protein is labelled with Fc Tag,His tag.
    原理
    Recombinant Human Activin Receptor 2A/Activin RIIA/ACVR2A (C-Fc-6His)
    序列
    AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPVDDIE GRMDEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSREEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH
    产品特性
    Recombinant Human Activin Receptor Type-2A/Activin RIIA is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala20-Pro134) of Human Activin RIIA fused with a FC-6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product ACVR2A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    ACVR2A (Activin A Receptor, Type IIA (ACVR2A))
    别名
    Activin Receptor Type-2A/Activin RIIA (ACVR2A 产品)
    别名
    ACVR2 Protein, ACVR2A Protein, XSTK9 Protein, actrii Protein, acvr2 Protein, ACTRII Protein, Acvr2 Protein, rActR-II Protein, actr2a Protein, acvr2a Protein, wu:fa02e10 Protein, ActrIIa Protein, TactrII Protein, activin A receptor type 2A Protein, activin A receptor type 2A L homeolog Protein, activin A receptor type 2Aa Protein, activin receptor IIA Protein, ACVR2A Protein, acvr2a Protein, Acvr2a Protein, acvr2a.L Protein, acvr2aa Protein
    Sub Type
    Fusionprotein
    背景
    Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
    Alternative Names: Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2
    分子量
    41.2 kDa
    UniProt
    P27037
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