ACE2 Protein (AA 18-740) (His tag)
(1 reference)-
- 抗原 See all ACE2 蛋白
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 18-740
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宿主
- 人
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资源
- 人细胞
- 标记
- This ACE2 protein is labelled with His tag.
- 应用范围
- Functional Studies (Func)
- 原理
- Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His)
- 序列
- QSTIEEQAKT FLDKFNHEAE DLFYQSSLAS WNYNTNITEE NVQNMNNAGD KWSAFLKEQS TLAQMYPLQE IQNLTVKLQL QALQQNGSSV LSEDKSKRLN TILNTMSTIY STGKVCNPDN PQECLLLEPG LNEIMANSLD YNERLWAWES WRSEVGKQLR PLYEEYVVLK NEMARANHYE DYGDYWRGDY EVNGVDGYDY SRGQLIEDVE HTFEEIKPLY EHLHAYVRAK LMNAYPSYIS PIGCLPAHLL GDMWGRFWTN LYSLTVPFGQ KPNIDVTDAM VDQAWDAQRI FKEAEKFFVS VGLPNMTQGF WENSMLTDPG NVQKAVCHPT AWDLGKGDFR ILMCTKVTMD DFLTAHHEMG HIQYDMAYAA QPFLLRNGAN EGFHEAVGEI MSLSAATPKH LKSIGLLSPD FQEDNETEIN FLLKQALTIV GTLPFTYMLE KWRWMVFKGE IPKDQWMKKW WEMKREIVGV VEPVPHDETY CDPASLFHVS NDYSFIRYYT RTLYQFQFQE ALCQAAKHEG PLHKCDISNS TEAGQKLFNM LRLGKSEPWT LALENVVGAK NMNVRPLLNY FEPLFTWLKD QNKNSFVGWS TDWSPYADQS IKVRISLKSA LGDKAYEWND NEMYLFRSSV AYAMRQYFLK VKNQMILFGE EDVRVANLKP RISFNFFVTA PKNVSDIIPR TEVEKAIRMS RSRINDAFRL NDNSLEFLGI QPTLGPPNQP PVSVDHHHHH H
- 产品特性
- Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 produced by transfected human cells is a secreted protein with sequence (Gln18-Ser740) of human ACE-2 fused with a polyhistidine tag at the C-terminus
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ACE2 蛋白
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Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag,AVI tag,Biotin)
ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS, Func
Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag)ACE2 宿主: Paguma larvata 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (Fc Tag)ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag,Biotin)ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag)ACE2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag)ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (His tag)ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (Fc-Avi Tag,Biotin)ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiotensin I Converting Enzyme 2 (ACE2) protein (mFc Tag)ACE2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Angiotensin I Converting Enzyme 2 (ACE2) protein (His-Avi Tag,Biotin)ACE2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
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- 说明
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Biological activity: Specific Activity is > 800 pmol/min/µg as measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH
- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 0.1 mM ZnCl2, 10 % Glycerol, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
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: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
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- 抗原
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- 别名
- ace-2 (ACE2 产品)
- 别名
- ACE1 Protein, CD143 Protein, DCP Protein, DCP1 Protein, ICH Protein, MVCD3 Protein, ACEH Protein, 2010305L05Rik Protein, zgc:92514 Protein, angiotensin I converting enzyme Protein, angiotensin I converting enzyme 2 Protein, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Protein, ACE Protein, ACE2 Protein, Ace2 Protein, ace2 Protein
- Sub Type
- Fusionprotein
- 背景
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Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Alternative Names: Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2 - 分子量
- 84.63 kDa
- UniProt
- Q9BYF1
- 途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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