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抗Rat (Rattus) ADAR 抗体:
抗Human ADAR 抗体:
抗Mouse (Murine) ADAR 抗体:
Human Polyclonal ADAR Primary Antibody for IF, IHC (p) - ABIN513112
Liu, Chen, Yeh, Li, Wu, Chen, Chen, Yeh: ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. in PLoS ONE 2014
Guinea Pig Polyclonal ADAR Primary Antibody for IHC, WB - ABIN2774647
Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study. in Journal of affective disorders 2008
Show all 2 Pubmed References
Human Polyclonal ADAR Primary Antibody for IHC, WB - ABIN2774648
Zhang, Liu, Jiang, Tian, Wang, Yu: Six novel mutations of the ADAR1 gene in Chinese patients with dyschromatosis symmetrica hereditaria. in Journal of dermatological science 2008
Show all 2 Pubmed References
The presence of ADA (显示 ADA 抗体) activity in zebrafish brain may be important to regulate the adenosine/inosine levels in the CNS of this species
These findings suggest a role of NS4A in the interaction of BVDV with ADAR that favors virus replication.
our data shows that ADAR is essential for proper temperature adaptation, a key behavior trait that is essential for survival of flies in the wild. Moreover, our results suggest a more general role of ADAR in regulating RNA secondary structures in vivo
Deficiencies in the RNA-editing gene Adar increase sleep due to synaptic dysfunction in glutamatergic neurons.
The study demonstrates that neuronal excitability is linked to dADAR expression levels in individual neurons.
loss of Adar increases quantal size, reduces the number of quanta of neurotransmitter released and perturbs the calcium dependence of synaptic release
results demonstrate a novel role for dADAR protein in rnp (显示 RNPC3 抗体)-4f 5'-UTR (显示 UTS2R 抗体) alternative intron splicing regulation which is consistent with a previously proposed model.
Data suggeset that RNA editing enzyme ADAR-mediated editing is more widespread than previously indicated and largely occurs cotranscriptionally.
the solution structure of the N-terminal dsRNA binding domain (dsRBD) of dADAR
Abolishing dADAR auto-regulation dramatically remodels the landscape of re-coding events in a site-specific manner.
network-wide temporal and spatial regulation of ADAR activity can tune the complex system of RNA-editing sites and modulate multiple ethologically relevant behavioral modalities.
Our study is the first to systematically characterize the temporal and spatial expression of full-length and truncated dADAR mRNA and protein isoforms during Drosophila embryogenesis.
ADAR copy number is negatively associated with apoptosis and several immune cell types' signatures.
CDK13 (显示 CDK13 抗体) RNA over-editing sites mediated by ADAR1 may serve as novel cancer driver events in HCC (显示 FAM126A 抗体) progression.
n this study, we found that a 28 year-old male patient harbouring a deleterious substitution of Leu1052Pro in the ADAR1 gene in a typical Dyschromatosis symmetrica hereditaria family. His mother suffered from the Dyschromatosis symmetrica hereditaria also owns the same mutation.
ADAR1 regulates post-transcriptional gene expression in gastric cancer through both RNA editing-dependent and editing-independent mechanisms.
Expansion of mutation spectrum in dyschromatosis symmetrica hereditaria by identifying eight novel ADAR1 mutations.
ADAR1 functions other than RNA editing are reviewed.
A novel function of ADAR1 as an inhibitor of L1 retrotransposition was demonstrated.
Data collected from our center strongly suggest that ADAR1 expression can effectively predict HCC (显示 FAM126A 抗体) patients' prognosis and an abnormal overexpression of ADAR1 is positively correlated with AR in HCC (显示 FAM126A 抗体).
Results implicate rare variants in the Aicardi-Goutieres syndrome genes ADAR and RNASEH2B (显示 RNASEH2B 抗体) and a type I interferon (显示 IFNA 抗体) signature in glioma and prostate carcinoma risk and tumorigenesis, consistent with a genetic basis underlying inflammation-driven malignant transformation in glioma and prostate carcinoma development.
The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK (显示 PTK2 抗体).
protein recoding arising from ADAR1-mediated editing is not essential for organismal homeostasis
These findings shed a new light on the vital regulatory role of ADAR1(Adenosine deaminase) in hepatic immune homeostasis, chiefly its inhibitory function on the crosstalk between the NFkappaB and type-I interferons signaling cascades, restraining the development of liver inflammation and fibrosis.
ADAR1-mediated RNA editing is essential for normal erythropoiesis.
Knockout of ADAR1 dramatically inhibited injury-induced neointima formation and restored vascular smooth muscle cell remodeling.
we identified a novel ADAR1-dependent protective contribution through which hepatocytes guard against aberrant cytosolic RLR (显示 DHX58 抗体)-RNA-sensing pathway mediated inflammatory reaction in response to acute liver IR.
Thus, Adarb1 (显示 ADARB1 抗体) and Adarb2 (显示 ADARB2 抗体) have nearly exclusive expression within brain tissue, while Adar has more appreciable expression across multiple tissues.
After fear conditioning protocol, mRNA expression of ADAR1 increased in amygdala and hippocampus.
ADAR1 is an essential molecule for maintaining adult liver homeostasis and, in turn, morphological and functional integrity.
The p150 (显示 ABL1 抗体) isoform of ADAR1 uniquely regulated the MDA5 (显示 IFIH1 抗体) pathway.
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
double-stranded RNA-specific adenosine deaminase
, dsRNA adenosine deaminase
, adenosine deaminase, RNA-specific
, RNA-specific adenosine deaminase
, adenosine deaminase acting on RNA
, adenosine deaminases acting on RNA
, hypoxia, anoxia, sensitive 2
, 136 kDa double-stranded RNA-binding protein
, adenosine deaminase acting on RNA 1-A
, interferon-induced protein 4
, interferon-inducible protein 4
, RNA adenosine deaminase 1
, RNA-specific adenosine deaminase p110 form
, RNA-specific adenosine deaminase p150 form