PRKAB1 抗体
(Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PRKAB1 抗体 (Thr283) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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| PRKAB1 抗体 (Internal Region) | 人 | 小鼠 Monoclonal |
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| PRKAB1 抗体 (AA 1-270) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 680) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 647) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 488) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 555) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (Cy3) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (Biotin) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (FITC) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (HRP) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (Cy5) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (Cy5.5) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (AA 201-270) (Cy7) | 人 | 兔 Polyclonal |
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| PRKAB1 抗体 (pSer108) (AbBy Fluor® 350) | 小鼠 | 兔 Polyclonal |
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| PRKAB1 抗体 (pSer108) (AbBy Fluor® 488) | 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Thr283
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8178
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-270
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 647
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 555
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 201-270
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- pSer108
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- pSer108
Latest Publications for our PRKAB1 抗体
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3817-27, (2004) (PubMed).
: "AMP-activated protein kinase plays a role in the control of food intake." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12005-8, (2004) (PubMed).
: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).
: "Posttranslational modifications of the 5'-AMP-activated protein kinase beta1 subunit." in: The Journal of biological chemistry, Vol. 272, Issue 39, pp. 24475-9, (1997) (PubMed).
: "Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 82, Issue 1, pp. 219-25, (1997) (PubMed).
: "Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase." in: The Journal of biological chemistry, Vol. 271, Issue 45, pp. 28445-50, (1996) (PubMed).
: "Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro." in: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10282-90, (1996) (PubMed).
: "C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3817-27, (2004) (PubMed).
: "AMP-activated protein kinase plays a role in the control of food intake." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12005-8, (2004) (PubMed).
: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).
: "Posttranslational modifications of the 5'-AMP-activated protein kinase beta1 subunit." in: The Journal of biological chemistry, Vol. 272, Issue 39, pp. 24475-9, (1997) (PubMed).
: "Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 82, Issue 1, pp. 219-25, (1997) (PubMed).
: "Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase." in: The Journal of biological chemistry, Vol. 271, Issue 45, pp. 28445-50, (1996) (PubMed).
: "Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro." in: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10282-90, (1996) (PubMed).
Aliases for PRKAB1 抗体
protein kinase AMP-activated non-catalytic subunit beta 1 (PRKAB1) 抗体protein kinase, AMP-activated, beta 1 non-catalytic subunit (Prkab1) 抗体
protein kinase AMP-activated non-catalytic subunit beta 1 (Prkab1) 抗体
protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog (prkab1.S) 抗体
protein kinase, AMP-activated, beta 1 non-catalytic subunit (prkab1) 抗体
protein kinase, AMP-activated, beta 1 non-catalytic subunit, b (prkab1b) 抗体
protein kinase, AMP-activated, beta 1 non-catalytic subunit, a (prkab1a) 抗体
1300015D22Rik 抗体
AMPK 抗体
AU021155 抗体
E430008F22 抗体
HAMPKb 抗体
MGC82489 抗体
prkab1 抗体
wu:fk93d05 抗体
wu:fw87e09 抗体
zgc:56652 抗体
zgc:76975 抗体
zgc:92228 抗体
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