anti-马 Glutamate Dehydrogenase 1 抗体 for Western Blotting

Recommended Glutamate Dehydrogenase 1 Antibody (supplied by: Log in to see )

抗原
Glutamate Dehydrogenase 1 (GLUD1) 抗体
  • GDH
  • gdh1
  • GDH 1
  • glud1
  • GLUD1
  • cb719
  • wu:fb16e02
  • wu:fb58f12
  • wu:fe37f03
  • wu:fj43f02
  • zgc:192851
  • zgc:55630
  • GDH1
  • GLUD
  • AI118167
  • Gdh-X
  • Glud
  • Gludl
  • Ac2-281
  • Gdh1
  • Gludeha
  • MRG-2
  • GLUTAMATE DECARBOXYLASE 1
  • GLUTAMATE DEHYDROGENASE 1
  • MRG7.13
  • MRG7_13
  • glutamate dehydrogenase 1
  • legdh1
  • glutamate dehydrogenase 1
  • glutamate dehydrogenase 1 S homeolog
  • glutamate dehydrogenase 1, mitochondrial
  • glutamate dehydrogenase 1b
  • glutamate dehydrogenase
  • GLUD1
  • GDH1
  • glud1
  • glud1.S
  • LOC693461
  • glud1b
  • Glud1
  • HACJB3_RS00320
  • LOC100587725
  • gdh1
抗原表位
N-Term
11
6
5
5
2
2
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 猪, 兔, 大鼠, 绵羊, 斑马鱼
66
34
26
24
3
3
3
3
2
2
1
1
1
1
1
1
1
宿主

72
17
12
克隆类型
多克隆
标记
非结合性
8
5
4
3
3
2
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
85
55
47
23
15
13
9
8
8
5
5
4
4
1
1
1
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产品编号 ABIN2782330
$ 319.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
19.802607 ABIN2782329 IHC WB Rabbit N-Term Log in to see Polyclonal 1
13 ABIN604748 IHC IHC (p) WB Rabbit IgG AA 182-231 Log in to see Polyclonal 0
10 ABIN1496046 ELISA IHC IHC (p) WB Goat AA 93-107 Log in to see Polyclonal 0

General

抗原 Glutamate Dehydrogenase 1 (GLUD1) 抗体
抗原表位 N-Term
(11), (6), (5), (5), (2), (2), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 猪, 兔, 大鼠, 绵羊, 斑马鱼
(66), (34), (26), (24), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
宿主
(72), (17), (12)
克隆类型
多克隆
标记 非结合性
(8), (5), (4), (3), (3), (2), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(85), (55), (47), (23), (15), (13), (9), (8), (8), (5), (5), (4), (4), (1), (1), (1)
Pubmed 3个引用可参考
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产品细节

目标详细情况 使用细节 贮存及处理 引用 图像
Blocking Peptide Blocking peptide for this product available: ABIN977478
序列 AKAGVKINPK NYTDNELEKI TRRFTMELAK KGFIGPGIDV PAPDMSTGER
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
产品特性 This is a rabbit polyclonal antibody against GLUD1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human GLUD1

目标详细情况

产品细节 使用细节 贮存及处理 引用 图像 回页首
抗原
别名 GLUD1 (GLUD1 Antibody 摘要)
背景 L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification.L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]). Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 M20867.1 1-51 52-3120 BC112946.1 16-3084
Alias Symbols: GDH, GDH1, GLUD, MGC132003
Protein Interaction Partner: FUS, UBC, DCP2, KLHL29, SUMO1, NEDD8, LSM1, ILK, CDK5, VTN, SEC62, STAT5A, ORM1, HPX, NR4A1, FN1, CRP, ASGR2, CUL3, ELAVL1, EBNA-LP, HDAC5, ICT1, GLUD1, DYNLL1, GOT2,
Protein Size: 558
分子量 56 kDa
基因ID 2746
NCBI登录号 NM_005271, NP_005262
UniProt Q5TDP6
途径 Positive Regulation of Peptide Hormone Secretion

使用细节

产品细节 目标详细情况 贮存及处理 引用 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 558 AA

限制 仅限研究用

贮存及处理

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状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

引用

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有引用在:

Spanaki, Kotzamani, Plaitakis: "Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions." in: Neurochemical research, Vol. 42, Issue 1, pp. 92-107, 2016

Spanaki, Kotzamani, Petraki, Drakos, Plaitakis: "Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues." in: Molecular and cellular endocrinology, Vol. 415, pp. 1-11, 2015

背景

Kawajiri, Okano, Kuno, Tokuhara, Hase, Inada, Tashiro, Miyazaki, Yamano: "Unregulated insulin secretion by pancreatic beta cells in hyperinsulinism/hyperammonemia syndrome: role of glutamate dehydrogenase, ATP-sensitive potassium channel, and nonselective cation channel." in: Pediatric research, Vol. 59, Issue 3, pp. 359-64, 2006

图像

产品细节 目标详细情况 使用细节 贮存及处理 引用 回页首
厂商提供的图像
 image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) lanes 5: rat kidney cordex lanes 6: rat kidney proximal tubules prepped from cortex...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: GLUD1 Sample Tissue: Rat Skeletal Muscle Antibody Dil...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) GLUD1 antibody - N-terminal region validated by WB using Fetal Liver Lysate at 1ug/ml.
Immunohistochemistry (IHC) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Immunohistochemistry with CORTEX/KIDNEY tissue
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: GLUD1 Sample Tissue: Human Fetal Liver Antibody Dilut...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: SERPINA3 Sample Type: Human Adult Placenta Antibody D...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: GNAS Sample Type: Human Fetal Heart Antibody Dilution...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: NOP56 Sample Type: Human Fetal Brain Antibody Dilutio...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: HIRIP3 Sample Type: 293T Antibody Dilution: 1.0ug/ml...
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Host: Rabbit Target Name: GLUD1 Sample Type: Human Fetal Liver Lane A: Primary...
Immunohistochemistry (IHC) image for anti-Glutamate Dehydrogenase 1 (GLUD1) (N-Term) antibody (ABIN2782330) Immunohistochemistry with pFA fixed human pancreas tissue tissue