PJA1 抗体
(Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))
This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
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Latest Publications for our PJA1 抗体
: "A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22541-6, (2002) (PubMed).
: "PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain." in: Genomics, Vol. 79, Issue 6, pp. 869-74, (2002) (PubMed).
: "PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain." in: Genomics, Vol. 79, Issue 6, pp. 869-74, (2002) (PubMed).
Aliases for PJA1 抗体
praja ring finger ubiquitin ligase 1 (PJA1) 抗体praja ring finger ubiquitin ligase 1 (Pja1) 抗体
PRAJA1 抗体
RNF70 抗体
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