PHF8 抗体
(PHD Finger Protein 8 (PHF8))
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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Latest Publications for our PHF8 抗体
: "Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway." in: Nature communications, Vol. 9, Issue 1, pp. 114, (2018) (PubMed).: "The HIF/PHF8/AR axis promotes prostate cancer progression." in: Oncogenesis, Vol. 5, Issue 12, pp. e283, (2016) (PubMed).
: "PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis." in: Cell research, Vol. 20, Issue 7, pp. 794-801, (2010) (PubMed).
: "Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development." in: Nature, Vol. 466, Issue 7305, pp. 503-7, (2010) (PubMed).
Aliases for PHF8 抗体
PHD finger protein 8 (Phf8) 抗体PHD finger protein 8 (PHF8) 抗体
PHD finger protein 8 (phf8) 抗体
9830141C09Rik 抗体
JHDM1F 抗体
mKIAA1111 抗体
MRXSSD 抗体
RGD1561065 抗体
ZNF422 抗体
zPHF8 抗体
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