PHGDH 抗体
(phosphoglycerate Dehydrogenase (PHGDH))
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PHGDH 抗体 (AA 1-533) | 人 | 小鼠 Monoclonal |
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| PHGDH 抗体 | 人 | 小鼠 Monoclonal |
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| PHGDH 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 264-533) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 249-277) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 2-251) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 140-168) | 人, 小鼠 | 兔 Polyclonal |
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| PHGDH 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 1-50) | 人, 小鼠 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 1-533) | 人 | 小鼠 Polyclonal |
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| PHGDH 抗体 (AA 1-533) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 249-277) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 1-534) | 人 | 小鼠 Monoclonal |
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| PHGDH 抗体 (AA 362-411) | 人, 小鼠, 大鼠, Hamster, 猴 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 254-303) | 人, 小鼠, 大鼠, 马, Pig, 兔, Hamster, Bat | 兔 Polyclonal |
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| PHGDH 抗体 (N-Term) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| PHGDH 抗体 (Middle Region) | 人, 小鼠, 大鼠, 马, Pig, 兔, 犬, Cow, 豚鼠, 斑马鱼 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 101-200) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| PHGDH 抗体 (AA 101-200) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 有验证图片)
- ISt (Immunostaining: 有验证图片)
- ELISA (ELISA: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
1 reference - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4A3-1D6
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-533
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 24GB14070
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 264-533
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB20882
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 140-168, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB20883
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 249-277
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2-251
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 140-168
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-50
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-533
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-533
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 249-277
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4A3-1D6
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-534
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 马, Pig, 兔, Hamster, Bat
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 254-303
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8396
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 马, Pig, 兔, 犬, Cow, 豚鼠, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 101-200
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 101-200
Latest Publications for our PHGDH 抗体
: "Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 21, pp. 5392-5406, (2018) (PubMed).
: "Systematic analysis of mRNA expression profiles in NSCLC cell lines to screen metastasis-related genes." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5093-5103, (2017) (PubMed).
: "PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis." in: Cancer research, Vol. 76, Issue 15, pp. 4430-42, (2016) (PubMed).
: "An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation." in: Cancer & metabolism, Vol. 3, pp. 5, (2015) (PubMed).
: "Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3667-79, (2015) (PubMed).
: "NRF2 regulates serine biosynthesis in non-small cell lung cancer." in: Nature genetics, Vol. 47, Issue 12, pp. 1475-81, (2015) (PubMed).
: "Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells." in: Nature, Vol. 493, Issue 7433, pp. 542-6, (2013) (PubMed).
: "Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis." in: PLoS genetics, Vol. 8, Issue 3, pp. e1002573, (2012) (PubMed).
: "Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. ..." in: Nature, Vol. 476, Issue 7360, pp. 346-50, (2011) (PubMed).
: "Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis." in: Breast cancer research and treatment, Vol. 125, Issue 2, pp. 421-30, (2010) (PubMed).
: "Systematic analysis of mRNA expression profiles in NSCLC cell lines to screen metastasis-related genes." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5093-5103, (2017) (PubMed).
: "PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis." in: Cancer research, Vol. 76, Issue 15, pp. 4430-42, (2016) (PubMed).
: "An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation." in: Cancer & metabolism, Vol. 3, pp. 5, (2015) (PubMed).
: "Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3667-79, (2015) (PubMed).
: "NRF2 regulates serine biosynthesis in non-small cell lung cancer." in: Nature genetics, Vol. 47, Issue 12, pp. 1475-81, (2015) (PubMed).
: "Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells." in: Nature, Vol. 493, Issue 7433, pp. 542-6, (2013) (PubMed).
: "Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis." in: PLoS genetics, Vol. 8, Issue 3, pp. e1002573, (2012) (PubMed).
: "Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. ..." in: Nature, Vol. 476, Issue 7360, pp. 346-50, (2011) (PubMed).
: "Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis." in: Breast cancer research and treatment, Vol. 125, Issue 2, pp. 421-30, (2010) (PubMed).
Aliases for PHGDH 抗体
phosphoglycerate dehydrogenase (phgdh) 抗体D-3-phosphoglycerate dehydrogenase (EDA9) 抗体
D-3-phosphoglycerate dehydrogenase (serA) 抗体
D-3-phosphoglycerate dehydrogenase (Sthe_2284) 抗体
D-3-phosphoglycerate dehydrogenase (Dacet_1260) 抗体
D-3-phosphoglycerate dehydrogenase (Mrub_0173) 抗体
phosphoglycerate dehydrogenase (MMAH_RS07650) 抗体
D-3-phosphoglycerate dehydrogenase (Arnit_0487) 抗体
D-3-phosphoglycerate dehydrogenase (Ndas_0174) 抗体
D-3-phosphoglycerate dehydrogenase (Mesil_2386) 抗体
D-3-phosphoglycerate dehydrogenase (Slip_0010) 抗体
D-3-phosphoglycerate dehydrogenase (Trad_0302) 抗体
D-3-phosphoglycerate dehydrogenase (Acear_0027) 抗体
D-3-phosphoglycerate dehydrogenase (Mahau_0665) 抗体
phosphoglycerate dehydrogenase (MZHIL_RS05165) 抗体
D-3-phosphoglycerate dehydrogenase (Mesop_1331) 抗体
D-3-phosphoglycerate dehydrogenase (Thein_0855) 抗体
3-phosphoglycerate dehydrogenase (Phgdh) 抗体
phosphoglycerate dehydrogenase (PHGDH) 抗体
phosphoglycerate dehydrogenase (Phgdh) 抗体
3-PGDH 抗体
3PGDH 抗体
4930479N23 抗体
A10 抗体
ECK2909 抗体
embryo sac development arrest 9 抗体
F10M10.7 抗体
fb38f06 抗体
JW2880 抗体
PDG 抗体
PGAD 抗体
PGD 抗体
PGDH 抗体
SERA 抗体
wu:fb38f06 抗体
zgc:65956 抗体
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