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PHD1 抗体

(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011].
PHD1 抗体  (AA 283-407) PHD1 抗体  (AA 283-407) PHD1 抗体 (AA 283-407) (ABIN7151444)

EGLN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PHD1 抗体  (AA 58-107) PHD1 抗体  (AA 58-107) PHD1 抗体 (AA 58-107) (ABIN6736715)

EGLN2 适用: 人, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

PHD1 抗体  (AA 150-250) PHD1 抗体  (AA 150-250) PHD1 抗体 (AA 150-250) (ABIN1679676)

EGLN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

PHD1 抗体 by 适用

Find PHD1 抗体 for a variety of species such as anti-Human PHD1, anti-Mouse PHD1, anti-Rat PHD1. The species listed below are among those available. Click on a link to go to the corresponding products.

PHD1 抗体 by 应用范围

Find PHD1 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find PHD1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PHD1 抗体 by 抗原表位

Find PHD1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PHD1 抗体 by 克隆形成能力

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PHD1 抗体 by 克隆

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Popular PHD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7151444
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Human
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6736715
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN1679676
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN530187
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652648
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1678674
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
Cat. No. ABIN6261465
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6740396
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN6756541
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6569199
Quantity 200 μL
Datasheet Datasheet
Reactivity Dog, Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2778438
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2775992
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2778439
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (1)
  • (1)
Cat. No. ABIN453633
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN705896
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PHD1 抗体

Zhang, Peng, Dai, Gan, Nie, Wei, Hu, Guo: "Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells." in: Cancer letters, Vol. 390, pp. 11-20, (2017) (PubMed).

Chu, Jones: "Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat." in: Neurochemical research, Vol. 41, Issue 3, pp. 515-22, (2016) (PubMed).

Takada, Zhuang, Inuzuka, Zhang, Zurlo, Zhang, Zhang: "EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor." in: Oncotarget, Vol. 8, Issue 4, pp. 6787-6795, (2016) (PubMed).

Deschoemaeker, Di Conza, Lilla, Martín-Pérez, Mennerich, Boon, Hendrikx, Maddocks, Marx, Radhakrishnan, Prenen, Schneider, Myllyharju, Kietzmann, Vousden, Zanivan, Mazzone: "PHD1 regulates p53-mediated colorectal cancer chemoresistance." in: EMBO molecular medicine, Vol. 7, Issue 10, pp. 1350-65, (2015) (PubMed).

Högel, Miikkulainen, Bino, Jaakkola: "Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27." in: Molecular cancer, Vol. 14, pp. 143, (2015) (PubMed).

Zhang, Wang, Chen, Takada, Fan, Zheng, Wen, Liu, Wang, Pestell, Aird, Kaelin, Liu, Zhang: "EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer." in: The EMBO journal, Vol. 34, Issue 23, pp. 2953-70, (2015) (PubMed).

Zheng, Zhai, Koivunen, Shin, Lu, Liu, Geisen, Chakraborty, Moslehi, Smalley, Wei, Chen, Chen, Beres, Zhang, Tsao, Brenner, Zhang, Fan, DePinho, Paik, Gygi, Kaelin, Zhang: "Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase." in: Genes & development, Vol. 28, Issue 13, pp. 1429-44, (2014) (PubMed).

Yogev, Lagos, Enver, Boshoff: "Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells." in: PLoS pathogens, Vol. 10, Issue 9, pp. e1004400, (2014) (PubMed).

Tan, Prosser, Vanags, Monger, Ng, Bursill: "High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 206-17, (2014) (PubMed).

Rawluszko, Bujnicka, Horbacka, Krokowicz, Jagodziński: "Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer." in: BMC cancer, Vol. 13, pp. 526, (2014) (PubMed).

Aliases for PHD1 抗体

egl-9 family hypoxia-inducible factor 1 (egln1) 抗体
egl-9 family hypoxia inducible factor 2 (EGLN2) 抗体
Egl nine homolog 2 (egln2) 抗体
egl-9 family hypoxia-inducible factor 2 L homeolog (egln2.L) 抗体
egl-9 family hypoxia-inducible factor 2 (Egln2) 抗体
0610011A13Rik 抗体
C85656 抗体
egln2 抗体
EIT6 抗体
Hif-p4h-1 抗体
HIF-PH1 抗体
HIFPH1 抗体
HPH-1 抗体
HPH-3 抗体
Ier4 抗体
PHD-1 抗体
PHD1 抗体
Phd1 抗体
phd2 抗体
SM-20 抗体
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