(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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Latest Publications on our PHD1 Products: "Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells." in: Cancer letters, Vol. 390, pp. 11-20, (2017) (PubMed).
: "Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat." in: Neurochemical research, Vol. 41, Issue 3, pp. 515-22, (2016) (PubMed).
: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." in: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
: "EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor." in: Oncotarget, Vol. 8, Issue 4, pp. 6787-6795, (2016) (PubMed).
: "PHD1 regulates p53-mediated colorectal cancer chemoresistance." in: EMBO molecular medicine, Vol. 7, Issue 10, pp. 1350-65, (2015) (PubMed).
: "Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27." in: Molecular cancer, Vol. 14, pp. 143, (2015) (PubMed).
: "EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer." in: The EMBO journal, Vol. 34, Issue 23, pp. 2953-70, (2015) (PubMed).
: "Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase." in: Genes & development, Vol. 28, Issue 13, pp. 1429-44, (2014) (PubMed).
: "Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells." in: PLoS pathogens, Vol. 10, Issue 9, pp. e1004400, (2014) (PubMed).
: "High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 206-17, (2014) (PubMed).
Synonyms and alternative names related to PHD1egl-9 family hypoxia-inducible factor 1 (egln1), egl-9 family hypoxia inducible factor 2 (EGLN2), Egl nine homolog 2 (egln2), egl-9 family hypoxia-inducible factor 2 L homeolog (egln2.L), egl-9 family hypoxia-inducible factor 2 (Egln2), 0610011A13Rik, C85656, egln2, EIT6, Hif-p4h-1, HIF-PH1, HIFPH1, HPH-1, HPH-3, Ier4, PHD-1, PHD1, Phd1, phd2, SM-20
Protein level used designations for PHD1
- EGL nine homolog 2
- egl nine homolog 2
- Egl nine homolog 2
- EGL nine (C.elegans) homolog 2
- egl nine homolog 2 (C. elegans)
- egl nine homolog 2-like
- HIF-prolyl hydroxylase 1
- hypoxia-inducible factor prolyl hydroxylase 1
- immediate early response 4
- prolyl hydroxylase domain-containing protein 1
- HIF-1alpha prolyl-4-hydroxylase-1
- estrogen-induced tag 6
- PHAP III
- PHAP I