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PHF1 产品

(PHD Finger Protein 1 (PHF1))

Categories

This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].

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Featured PHF1 Categories

PHF1 抗体

High quality antibodies with extensive validation data.

PHF1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PHF1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PHF1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (6)
Cat. No. ABIN518847
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7163042
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (2)
Cat. No. ABIN562208
Quantity 100 μg
Datasheet Datasheet

Recommended PHF1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969245
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1147608
Quantity 96 tests
Datasheet Datasheet

Recommended PHF1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314874
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314873
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094574
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PHF1 Products

Yang, Wang, Zhang, Gao, Wang, Yu, Zhang, Jiang, Hexige, Hong, Yasui, Liu, Huang, Yu: "Polycomb group protein PHF1 regulates p53-dependent cell growth arrest and apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 529-39, (2013) (PubMed).

Wang, Cheng, Qin, Jia: "Val97Leu mutant presenilin-1 induces tau hyperphosphorylation and spatial memory deficit in mice and the underlying mechanisms." in: Journal of neurochemistry, Vol. 121, Issue 1, pp. 135-45, (2012) (PubMed).

Hong, Jiang, Lan, Nakajima, Kanno, Koseki, Yasui: "A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell." in: Nucleic acids research, Vol. 36, Issue 9, pp. 2939-47, (2008) (PubMed).

Lazarov, Morfini, Pigino, Gadadhar, Chen, Robinson, Ho, Brady, Sisodia: "Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 26, pp. 7011-20, (2007) (PubMed).

Synonyms and alternative names related to PHF1

PHD finger protein 1 L homeolog (phf1.L), PHD finger protein 1 (PHF1), PHD finger protein 1 (Phf1), AW557215, D17Ertd455e, hPHF1, mPcl1, MTF2L2, pcl1, PCL1, PHF2, Tctex-3, Tctex3, TDRD19C, xpcl1

Protein level used designations for PHF1

  • PHD finger protein 1
  • polycomblike PCL1
  • PHD finger protein 1-like
  • hPCl1
  • polycomb-like protein 1
  • tudor domain containing 19C
  • t-complex testis-expressed 3
  • T-complex testis-expressed 3
  • polycomb-like 1
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