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PHF6 产品

(PHD Finger Protein 6 (PHF6))

Categories

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms. [provided by RefSeq, Jun 2010].

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Featured PHF6 Categories

PHF6 抗体

High quality antibodies with extensive validation data.

PHF6 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PHF6 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PHF6 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP, IF
Validations
  • (4)
Cat. No. ABIN7163056
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6242524
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7251841
Quantity 200 μL
Datasheet Datasheet

Recommended PHF6 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969247
Quantity 96 tests
Datasheet Datasheet

Recommended PHF6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314904
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314902
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085902
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PHF6 Products

Xiang, Wang, Xia, Chen: "The depletion of PHF6 decreases the drug sensitivity of T-cell acute lymphoblastic leukemia to prednisolone." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 2210-2217, (2019) (PubMed).

Cheng, Deng, Ikeuchi, Yuede, Li, Rensing, Huang, Baldridge, Maloney, Dougherty, Constantino, Jahani-Asl, Wong, Wozniak, Wang, Klyachko, Bonni: "Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome." in: Cell reports, Vol. 25, Issue 6, pp. 1404-1414.e6, (2018) (PubMed).

Meacham, Lawton, Soto-Feliciano, Pritchard, Joughin, Ehrenberger, Fenouille, Zuber, Williams, Young, Hemann: "A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth." in: Genes & development, Vol. 29, Issue 5, pp. 483-8, (2015) (PubMed).

Pontén, Jirström, Uhlen: "The Human Protein Atlas--a tool for pathology." in: The Journal of pathology, Vol. 216, Issue 4, pp. 387-93, (2008) (PubMed).

Synonyms and alternative names related to PHF6

PHD finger protein 6 (phf6), PHD finger protein 6 L homeolog (phf6.L), PHD finger protein 6 (PHF6), PHD finger protein 6 (Phf6), 2700007B13Rik, 4931428F02Rik, BFLS, BORJ, CENP-31, mKIAA1823, wu:fa22g03, zgc:55403

Protein level used designations for PHF6

  • PHD finger protein 6
  • PHD-like zinc finger protein
  • centromere protein 31
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