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Insulin (INS) (AA 9-23) Peptide

INS
产品编号 ABIN987527
发货至: 中国
  • 抗原 See all Insulin (INS) products
    Insulin (INS)
    蛋白结构域
    AA 9-23
    序列
    One-letter code: SHLVEALYLV CGERG, Three-letter code: {Ser}{His}{Leu}{Val}{Glu}{Ala}{Leu}{Tyr}{Leu}{Val}{Cys}{Gly}{Glu}{Arg}{Gly
    产品特性
    Formula: C72H116N20O22S1
    纯度
    > 95 %
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    储存条件
    -20 °C
  • 抗原
    Insulin (INS)
    别名
    IDDM2 Peptide, ILPR Peptide, IRDN Peptide, MODY10 Peptide, ins1 Peptide, xins Peptide, ins1-a Peptide, Insulin Peptide, AA986540 Peptide, Ins-2 Peptide, InsII Peptide, Mody Peptide, Mody4 Peptide, proinsulin Peptide, zgc:109842 Peptide, igf2-A Peptide, ins Peptide, ins-a Peptide, ins-b Peptide, insulin Peptide, insulin precursor Peptide, insulin II Peptide, preproinsulin Peptide, insulin L homeolog Peptide, insulin S homeolog Peptide, INS Peptide, INS-IGF2 Peptide, ins Peptide, Ins Peptide, PIN Peptide, Ins2 Peptide, ins.L Peptide, ins.S Peptide
    背景
    This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic beta cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
    分子量
    1645.9
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