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Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (C-Term) Peptide

TNFRSF13C 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN985304
发货至: 中国
  • 抗原 See all TNFRSF13C products
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    蛋白结构域
    C-Term
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    PGISDATAPA WPPPGEDPGT TPPGHSVPVP ATELGSTELV TTKTAGPEQQ
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TNFRSF13C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    别名
    RGD1560810 Peptide, TNFRSF13C Peptide, BAFF-R Peptide, BAFFR Peptide, BROMIX Peptide, CD268 Peptide, CVID4 Peptide, prolixin Peptide, 2010006P15Rik Peptide, Baffr Peptide, Bcmd Peptide, Bcmd-1 Peptide, Bcmd1 Peptide, Lvis22 Peptide, TNF receptor superfamily member 13C Peptide, uncharacterized LOC746611 Peptide, tumor necrosis factor receptor superfamily, member 13c Peptide, TNFRSF13C Peptide, Tnfrsf13c Peptide, LOC746611 Peptide
    背景
    B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

    Alias Symbols: BAFF-R, BAFFR, CD268, MGC138235, CVID4, BROMIX, prolixin

    Protein Size: 184
    分子量
    20 kDa
    基因ID
    115650
    NCBI登录号
    NM_052945, NP_443177
    UniProt
    Q96RJ3
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