Serum Response Factor (SRF) Peptide
SRF
适用: 人, 小鼠
宿主: 合成
BP, ChIP, WB
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- 抗原 See all SRF products
- SRF (Serum Response Factor (SRF))
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SRF antibody (Catalog #: P100866_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SRF (Serum Response Factor (SRF))
- 别名
- AW049942 Peptide, AW240594 Peptide, MCM1 Peptide, SRFX Peptide, XSRF Peptide, srf-A Peptide, RGD1559787 Peptide, srf Peptide, srf1 Peptide, serum response factor Peptide, serum response factor L homeolog Peptide, serum response factor a Peptide, Srf Peptide, SRF Peptide, srf.L Peptide, srfa Peptide
- 背景
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SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
Alias Symbols: MCM1
Protein Interaction Partner: FHL1,FHL2,FHL3,FHL5,FOS,FOSL1,NFYA,ATF6,BARX2,CAMK2A,CASP3,CASP6,CASP7,CASP8,CASP9,CEBPB,CREB1,CREBBP,CRIP2,CSNK2A1,ELK1,ELK4,ETV4,FHL1,FHL2,FHL3,FHL5,FLI1,GATA4,GTF2F1,GTF2I,HMGA1,HOPX,MAPKAPK2,MINPP1,MKL1,MKL2,MYOCD,MYOD1,MYOG,NCOA1,NCOR2,NFYA,NKX2-3,NKX2-5,NKX3-1,OGT,PML,PRKDC,PRRX1,PYCARD,RELA,RPS6KA1,RXRA,RXRG,SRC,SRF,SRFBP1,SSRP1,TCF3,TEAD1,ASCC1,ASCC2,ASCC3,ATF6,CD63,CEBPB,CREBBP,ELK1,ELK4,FLI1,GATA4,GTF2F1,GTF2I,Gata2,Gata4,Gata6,Hmga1,Hmga2,MKL1,MKL2,MYOCD,MYOG,Mkl1,Mkl2,Myocd,NCOA6,NCOR2,NFYA,NKX3-1,Nkx2-5,PML,RARG,REL,RELA,RXRG,SMARCA4,SP1,SRC,SSRP1,Ssrp1,TEAD1
Protein Size: 508 - 分子量
- 52 kDa
- 基因ID
- 6722
- NCBI登录号
- NM_003131, NP_003122
- UniProt
- P11831
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