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Protein Kinase A, alpha (PRKACA) (N-Term) Peptide

PRKACA 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982208
发货至: 中国
  • 抗原 See all PRKACA products
    PRKACA (Protein Kinase A, alpha (PRKACA))
    蛋白结构域
    N-Term
    宿主
    资源
    • 8
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    MASNSSDVKE FLAKAKEDFL KKWESPAQNT AHLDQFERIK TLGTGSFGRV
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PRKACA Antibody(ARP57828_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PRKACA (Protein Kinase A, alpha (PRKACA))
    别名
    PKACA Peptide, Calpha Peptide, Cs-PKA Peptide, PKCA1 Peptide, PKA Peptide, PKCD Peptide, Pkaca Peptide, zgc:158799 Peptide, protein kinase cAMP-activated catalytic subunit alpha Peptide, protein kinase, cAMP dependent, catalytic, alpha Peptide, cAMP-dependent protein kinase catalytic subunit Peptide, protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a Peptide, PRKACA Peptide, Prkaca Peptide, kin-1 Peptide, prkacaa Peptide
    背景
    CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Alias Symbols: MGC102831, MGC48865, PKACA

    Protein Interaction Partner: NMT1,AANAT,ABCA1,ACCN2,ACLY,ADCY5,ADD1,ADD2,ADRBK1,AKAP14,AKAP8L,APC,ATF1,ATP2B1,AURKA,BAD,BCL2,BRAF,C11orf17,C7orf16,CACNA1C,CACNB2,CACNG2,CAD,CCND1,CDK16,CETN1,CFTR,CIITA,CLDN3,CREM,CSK,CUL5,DNAJC5,DSP,EEF2K,EGFR,EPB49,ESR1,ETV1,FOS,FXYD1,GABRR1,GFAP,GJ

    Protein Size: 343
    分子量
    40 kDa
    基因ID
    5566
    NCBI登录号
    NM_207518, NP_997401
    UniProt
    A8K8B9
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