NTRK3
(Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
蛋白结构域
C-Term
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-NTRK3 antibody (Catalog #: ARP51318_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Alias Symbols: TRKC, gp145(trkC)
Protein Interaction Partner: DOK5,DYNLL1,HTR2A,IRAK1,JUN,KIDINS220,MAPK1,MAPK3,NGFR,NGFRAP1,NTF3,PLCG1,PTPN1,RASGRF1,SHC1,SHC2,SQSTM1,FRS2,NTF3,PLCG1,PTPN1,SHC1,SQSTM1