A synthetic peptide for use as a blocking control in assays to test for specificity of NTRK3 antibody, Alternative Names: NTRK3 control peptide, NTRK3 antibody Blocking Peptide, Anti-NTRK3 Blocking Peptide, Neurotrophic Tyrosine Kinase Receptor Type 3 Blocking Peptide, TRKC Blocking Peptide, gp145(trkC) Blocking Peptide, NTRK3, NTRK-3, NTRK 3, NTRK-3 Blocking Peptide, NTRK 3 Blocking Peptide
NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.