Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (N-Term) Peptide
NFATC1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all NFATC1 products
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-NFATC1 antibody (Catalog #: ARP38742_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- 别名
- nf-atc Peptide, nfat2 Peptide, nfatc Peptide, si:ch211-198c22.2 Peptide, NFATC1 Peptide, 2210017P03Rik Peptide, AI449492 Peptide, AV076380 Peptide, NF-ATc Peptide, NFAT2 Peptide, NFATc Peptide, Nfatcb Peptide, NF-ATC Peptide, NF-ATc1 Peptide, NFAT Peptide, NFATmac Peptide, nuclear factor of activated T-cells 1 Peptide, nuclear factor of activated T-cells 1 L homeolog Peptide, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 Peptide, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 Peptide, NFATC1 Peptide, nfatc1.L Peptide, nfatc1 Peptide, Nfatc1 Peptide
- 背景
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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: EP300,GNB2L1,MAPK14,PIM1,PPP3R1,PRKCA,SPI1,EGR1,EGR2,PIM1
Protein Size: 716 - 分子量
- 78 kDa
- 基因ID
- 4772
- NCBI登录号
- NM_172390, NP_765978
- UniProt
- Q2M1S3
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