Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1) (Middle Region) Peptide
MTHFD1
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all MTHFD1 products
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MTHFD1 antibody (Catalog #: ARP46147_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))
- 别名
- MTHFC Peptide, MTHFD Peptide, Tb07.27M11.970 Peptide, Dcs Peptide, E430024A07Rik Peptide, Mthfd Peptide, GB13160 Peptide, cb325 Peptide, fc29f07 Peptide, mthfd1 Peptide, wu:fc29f07 Peptide, zgc:55597 Peptide, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Peptide, C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase, cytoplasmic Peptide, putative C-1-tetrahydrofolate synthase,cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b Peptide, c-1-tetrahydrofolate synthase, cytoplasmic Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog Peptide, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase Peptide, MTHFD1 Peptide, Mthfd1 Peptide, Tc00.1047053509509.20 Peptide, Tc00.1047053511741.50 Peptide, Tc00.1047053511517.60 Peptide, Tc00.1047053508207.240 Peptide, Tb927.7.1600 Peptide, LINJ_26_0310 Peptide, LBRM_26_0350 Peptide, LMJF_26_0320 Peptide, mthfd1l Peptide, LOC550749 Peptide, mthfd1b Peptide, Tsp_00651 Peptide, mthfd1.L Peptide, mthfd1 Peptide, LOC589933 Peptide, LOC100634307 Peptide
- 背景
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MTHFD1 possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MTHFC, MTHFD
Protein Interaction Partner: MTHFD1,MCC,TRAF6,WDR8
Protein Size: 935 - 分子量
- 101 kDa
- 基因ID
- 4522
- NCBI登录号
- NM_005956, NP_005947
- UniProt
- P11586
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