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MTHFD1 产品

(Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

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This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008].

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Featured MTHFD1 Categories

MTHFD1 抗体

High quality antibodies with extensive validation data.

MTHFD1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MTHFD1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MTHFD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (5)
Cat. No. ABIN950021
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN518072
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC
Validations
  • (3)
Cat. No. ABIN7074609
Quantity 100 μL
Datasheet Datasheet

Recommended MTHFD1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1124329
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1124331
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1124330
Quantity 96 tests
Datasheet Datasheet

Recommended MTHFD1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311552
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090099
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127696
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MTHFD1 Products

Liu, Shah, Fan, Park, Wellen, Rabinowitz: "Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage." in: Nature chemical biology, Vol. 12, Issue 5, pp. 345-52, (2016) (PubMed).

Germain, Chatel-Chaix, Gagné, Bonneil, Thibault, Pradezynski, de Chassey, Meyniel-Schicklin, Lotteau, Baril, Lamarre: "Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 1, pp. 184-203, (2014) (PubMed).

Thangavel, Seelan, Lakshmanan, Vadnal, Stagner, Parthasarathy, Casanova, El-Mallakh, Parthasarathy: "Proteomic analysis of rat prefrontal cortex after chronic valproate treatment." in: Journal of neuroscience research, Vol. 92, Issue 7, pp. 927-36, (2014) (PubMed).

Tyleckova, Hrabakova, Mairychova, Halada, Radova, Dzubak, Hajduch, Gadher, Kovarova: "Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs." in: International journal of molecular sciences, Vol. 13, Issue 12, pp. 15536-64, (2013) (PubMed).

Dorszewska, Florczak, Rozycka, Kempisty, Jaroszewska-Kolecka, Chojnacka, Trzeciak, Kozubski: "Oxidative DNA damage and level of thiols as related to polymorphisms of MTHFR, MTR, MTHFD1 in Alzheimer's and Parkinson's diseases." in: Acta neurobiologiae experimentalis, Vol. 67, Issue 2, pp. 113-29, (2007) (PubMed).

Synonyms and alternative names related to MTHFD1

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1), methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (Mthfd1), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053509509.20), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053511741.50), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053511517.60), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053508207.240), C-1-tetrahydrofolate synthase, cytoplasmic (Tb927.7.1600), putative C-1-tetrahydrofolate synthase, cytoplasmic (LINJ_26_0310), putative C-1-tetrahydrofolate synthase,cytoplasmic (LBRM_26_0350), putative C-1-tetrahydrofolate synthase,cytoplasmic (LMJF_26_0320), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like (mthfd1l), methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase (Mthfd1), C-1-tetrahydrofolate synthase, cytoplasmic (LOC550749), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b (mthfd1b), c-1-tetrahydrofolate synthase, cytoplasmic (Tsp_00651), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog (mthfd1.L), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (mthfd1), C-1-tetrahydrofolate synthase, cytoplasmic (LOC589933), C-1-tetrahydrofolate synthase, cytoplasmic (LOC100634307), cb325, Dcs, E430024A07Rik, fc29f07, GB13160, MTHFC, MTHFD, Mthfd, mthfd1, Tb07.27M11.970, wu:fc29f07, zgc:55597

Protein level used designations for MTHFD1

  • 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase
  • C-1-tetrahydrofolate synthase, cytoplasmic
  • C1-THF synthase
  • cytoplasmic C-1-tetrahydrofolate synthase
  • C1-tetrahydrofolate synthase
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
  • methylenetetrahydrofolate dehydrogenase 1
  • pugilist
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
  • c-1-tetrahydrofolate synthase, cytoplasmic
  • formyltetrahydrofolate synthetase
  • methenyltetrahydrofolate cyclohydrolase
  • mthfd1 protein
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
  • c-1-tetrahydrofolate synthase, cytoplasmic-like
  • LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic
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