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MTAP 产品

(Methylthioadenosine phosphorylase (MTAP))
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008].

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Featured MTAP Categories

MTAP 抗体

High quality antibodies with extensive validation data.

MTAP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MTAP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MTAP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN561859
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN6144119
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN7268498
Quantity 100 μL
Datasheet Datasheet

Recommended MTAP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957799
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957800
Quantity 96 tests
Datasheet Datasheet

Recommended MTAP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1311524
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311528
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311526
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MTAP Products

Yang, Lu, Yu, Sun, Guo, Li, Guan: "Quantitative Analysis of Differential Proteome Expression in Epithelial-to-Mesenchymal Transition of Bladder Epithelial Cells Using SILAC Method." in: Molecules (Basel, Switzerland), Vol. 21, Issue 1, pp. 84, (2016) (PubMed).

Yang, Gee, Gee, Zurita-Lopez, Khare, Clarke, Mamula: "Lupus autoimmunity altered by cellular methylation metabolism." in: Autoimmunity, Vol. 46, Issue 1, pp. 21-31, (2013) (PubMed).

Rose, Poliseno, Wang, Clark, Pearlman, Wang, Vega Y Saenz de Miera, Medicherla, Christos, Shapiro, Pavlick, Darvishian, Zavadil, Polsky, Hernando, Ostrer, Osman: "Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression." in: Cancer research, Vol. 71, Issue 7, pp. 2561-71, (2011) (PubMed).

Newton-Bishop, Chang, Iles, Taylor, Bakker, Chan, Leake, Karpavicius, Haynes, Fitzgibbon, Elliott, Kanetsky, Harland, Barrett, Bishop: "Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 8, pp. 2043-54, (2010) (PubMed).

Zhang, Cheng, Yan, Chen, Wang, Yang: "[Association between methylthioadenosine phosphorylase gene single nucleotide polymorphisms and myocardial infarction in Chinese Han ethnicity]." in: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, Vol. 31, Issue 1, pp. 83-6, (2010) (PubMed).

Huang, Li, Yu, Chou, Tzeng, Hu, Uen, Tian, Wang, Fang, Huang, Wei, Wu, Li: "Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6963-72, (2009) (PubMed).

Belenky, Christensen, Gazzaniga, Pletnev, Brenner: "Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 158-64, (2008) (PubMed).

Synonyms and alternative names related to MTAP

methylthioadenosine phosphorylase (MTAP), methylthioadenosine phosphorylase (Mtap), methylthioadenosine phosphorylase (mtaP), methylthioadenosine phosphorylase (MMAH_RS04260), 5'-methylthioadenosine phosphorylase (TAGG_RS05050), methylthioadenosine phosphorylase (Toce_0364), 5'-methylthioadenosine phosphorylase (VDIS_RS03165), methylthioadenosine phosphorylase (MFER_RS02485), methylthioadenosine phosphorylase (Intca_0886), 5'-methylthioadenosine phosphorylase (DESMU_RS05370), methylthioadenosine phosphorylase (Dester_1490), 6-oxopurine nucleoside phosphorylase (ARCVE_RS05445), methylthioadenosine phosphorylase (Mahau_1873), methylthioadenosine phosphorylase (MZHIL_RS01440), methylthioadenosine phosphorylase (mtap), methylthioadenosine phosphorylase L homeolog (mtap.L), 1300019I21Rik, BDMF, c86fus, Cc1-6, DMSFH, DMSMFH, LGMBF, MSAP, mtap, MTAPase, zgc:66012

Protein level used designations for MTAP

  • 5'-methylthioadenosine phosphorylase
  • MTA phosphorylase
  • MTAPase
  • MeSAdo phosphorylase
  • S-methyl-5'-thioadenosine phosphorylase
  • methylthioadenosine phosphorylase
  • CG4802-like
  • methylthioadenosine phosphorylase L homeolog
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