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Mismatch Repair Protein 2 (MSH2) (N-Term) Peptide

MSH2 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN980286
发货至: 中国
  • 抗原 See all MSH2 products
    MSH2 (Mismatch Repair Protein 2 (MSH2))
    蛋白结构域
    N-Term
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-MSH2 antibody (Catalog #: ARP41351_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    MSH2 (Mismatch Repair Protein 2 (MSH2))
    别名
    COCA1 Peptide, FCC1 Peptide, HNPCC Peptide, HNPCC1 Peptide, LCFS2 Peptide, AI788990 Peptide, wu:fc06b02 Peptide, wu:fc13e09 Peptide, zgc:55333 Peptide, ATMSH2 Peptide, MUTS homolog 2 Peptide, msh2 Peptide, mutS homolog 2 Peptide, mutS homolog 2 (E. coli) Peptide, MUTS homolog 2 Peptide, mutS homolog 2 L homeolog Peptide, MutS protein homolog 2 Peptide, MSH2 Peptide, Msh2 Peptide, msh2 Peptide, msh2.L Peptide
    背景
    MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: COCA1, FCC1, HNPCC, HNPCC1, LCFS2

    Protein Interaction Partner: E2F1,E2F1,E2F3,E2F4,BRCA1,EXO1,EXO1,MAX,MSH3,MSH6,MSH6,ATR,ATRIP,BARD1,CHEK2,CREBBP,EXO1,MAX,MSH3,MSH6,PCNA,SMC1A,AIRE,ATM,ATR,ATRIP,BARD1,BLM,BRCA1,BTBD12,CHEK1,CHEK2,EXO1,MAX,MLH1,MRE11A,MSH2,MSH3,MSH6,MYC,NBN,OTUB1,PCNA,PMS2,PTP4A3,RAD50,RFC1

    Protein Size: 934
    分子量
    105 kDa
    基因ID
    4436
    NCBI登录号
    NM_000251, NP_000242
    UniProt
    P43246
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