This is a synthetic peptide designed for use in combination with anti-MSH2 antibody (Catalog #: ARP41350_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
Alias Symbols: FCC1, COCA1, HNPCC, LCFS2, HNPCC1
Protein Interaction Partner: E2F1,E2F1,E2F3,E2F4,BRCA1,EXO1,EXO1,MAX,MSH3,MSH6,MSH6,ATR,ATRIP,BARD1,CHEK2,CREBBP,EXO1,MAX,MSH3,MSH6,PCNA,SMC1A,AIRE,ATM,ATR,ATRIP,BARD1,BLM,BRCA1,BTBD12,CHEK1,CHEK2,EXO1,MAX,MLH1,MRE11A,MSH2,MSH3,MSH6,MYC,NBN,OTUB1,PCNA,PMS2,PTP4A3,RAD50,RFC1