MutL Homolog 1 (MLH1) (N-Term) Peptide
MLH1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MLH1 products
- MLH1 (MutL Homolog 1 (MLH1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MLH1 antibody (Catalog #: ARP56076_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MLH1 (MutL Homolog 1 (MLH1))
- 别名
- CG11482 Peptide, Dmel\\CG11482 Peptide, dmlh-1 Peptide, dmlh1 Peptide, zgc:66301 Peptide, MLH1 Peptide, LOC100232198 Peptide, 1110035C23Rik Peptide, AI317206 Peptide, AI325952 Peptide, AI561766 Peptide, COCA2 Peptide, FCC2 Peptide, HNPCC Peptide, HNPCC2 Peptide, hMLH1 Peptide, mutL homolog 1 Peptide, CG11482 gene product from transcript CG11482-RB Peptide, mutL homolog 1 S homeolog Peptide, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) Peptide, DNA mismatch repair protein Mlh1 Peptide, MLH1 Peptide, Mlh1 Peptide, mlh1.S Peptide, mlh1 Peptide, LOC588545 Peptide
- 背景
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This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC.This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1
Protein Interaction Partner: E2F1,E2F4,BLM,EXO1,EXO1,MBD4,MLH3,MSH4,MYC,PMS1,PMS2,AP2B1,BLM,BRCA1,CASP3,EXO1,FRMD6,MBD4,MLH3,MSH4,MYC,PMS1,PMS2,RAD9A,TRIM29,UBOX5,ZC3H11A,AIFM1,AMOT,AP2B1,ATAD3A,ATAD3B,ATM,ATP5A1,BLM,BRCA1,BRIP1,DOCK7,EXO1,EXO1,FRMD6,KPNA2,KPNB1,MBD4,MLH3,MRE11A,MSH2,MSH3,MSH4,MSH6,MTMR15,MYC,NBN,NTG2,PIK3C2A,PMS1,PMS2,PPP2R1A,PPP2R2A,PPP2R2B,PPP2R2D,PPP3CB,PPP3CC,PRKDC,PSD3,PYGB,RAD50,RFC1,RUVBL1,RUVBL2,SGS1,SMC1A,TRIM29,UBAP2L,UBC,UBOX5,WDR61,XRN1,YLPM1,ZC3H11A
Protein Size: 756 - 分子量
- 84 kDa
- 基因ID
- 4292
- NCBI登录号
- NM_000249, NP_000240
- UniProt
- P40692
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