MutL Homolog 1 (MLH1) (Middle Region) Peptide
MLH1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MLH1 products
- MLH1 (MutL Homolog 1 (MLH1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- AAKNQSLEGD TTKGTSEMSE KRGPTSSNPR KRHREDSDVE MVEDDSRKEM
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- MLH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MLH1 (MutL Homolog 1 (MLH1))
- 别名
- CG11482 Peptide, Dmel\\CG11482 Peptide, dmlh-1 Peptide, dmlh1 Peptide, zgc:66301 Peptide, MLH1 Peptide, LOC100232198 Peptide, 1110035C23Rik Peptide, AI317206 Peptide, AI325952 Peptide, AI561766 Peptide, COCA2 Peptide, FCC2 Peptide, HNPCC Peptide, HNPCC2 Peptide, hMLH1 Peptide, mutL homolog 1 Peptide, CG11482 gene product from transcript CG11482-RB Peptide, mutL homolog 1 S homeolog Peptide, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) Peptide, DNA mismatch repair protein Mlh1 Peptide, MLH1 Peptide, Mlh1 Peptide, mlh1.S Peptide, mlh1 Peptide, LOC588545 Peptide
- 背景
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This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Alias Symbols: FCC2, COCA2, HNPCC, hMLH1, HNPCC2
Protein Size: 515 - 基因ID
- 4292
- NCBI登录号
- NM_000249, NP_000240
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