Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (Middle Region) Peptide
ERCC8
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all ERCC8 products
- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
- 蛋白结构域
- Middle Region
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-ERCC8 antibody (Catalog #: ARP58570_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
- 别名
- zgc:103550 Peptide, CKN1 Peptide, CSA Peptide, UVSS2 Peptide, Ckn1 Peptide, 2410022P04Rik Peptide, 2810431L23Rik Peptide, 4631412O06Rik Peptide, B130065P18Rik Peptide, Csa Peptide, excision repair cross-complementation group 8 Peptide, ERCC excision repair 8, CSA ubiquitin ligase complex subunit Peptide, excision repaiross-complementing rodent repair deficiency, complementation group 8 Peptide, ercc8 Peptide, ERCC8 Peptide, Ercc8 Peptide
- 背景
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ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
Alias Symbols: CKN1, CSA
Protein Interaction Partner: CBR1,DDB1,ERCC6,GTF2H2,UQCRQ,XAB2,COPS5,COPS6,CUL4A,CUL4B,DDB1,XAB2
Protein Size: 396 - 分子量
- 44 kDa
- 基因ID
- 1161
- NCBI登录号
- NM_000082, NP_000073
- UniProt
- Q13216
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