This is a synthetic peptide designed for use in combination with anti-CD4 Antibody(ARP59105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alias Symbols: CD4mut
Protein Interaction Partner: CD4,env,CCR5,CD2,CD28,CD38,CD4,CD44,CD5,CD53,CD82,CTSD,CXCL12,CXCR4,DPP4,FCGR3A,HLA-DPA1,HLA-DQA2,HLA-DQB1,IL16,IL2RA,KCNAB2,LAT,LCK,LGALS1,MARCH4,PI4KA,PIK3R1,PIP,PTPRC,SELL,SPG21,TFRC,TNFRSF10A,UNC119,BTRC,CCR5,CD81,CD82,CXCR4,EPS15,IL16,KCNAB2,LCK,LGAL