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Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (Middle Region) Peptide

CACNB4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN974381
发货至: 中国
  • 抗原 See all CACNB4 products
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CACNB4 antibody (Catalog #: ARP36763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
    别名
    CAB4 Peptide, CACNLB4 Peptide, EA5 Peptide, EIG9 Peptide, EJM Peptide, EJM4 Peptide, EJM6 Peptide, 3110038O15Rik Peptide, Cchb4 Peptide, lethargic Peptide, lh Peptide, CACNB4 Peptide, cacnb4.2 Peptide, calcium voltage-gated channel auxiliary subunit beta 4 Peptide, calcium channel, voltage-dependent, beta 4 subunit Peptide, calcium channel, voltage-dependent, beta 4a subunit Peptide, CACNB4 Peptide, Cacnb4 Peptide, cacnb4.1 Peptide, cacnb4 Peptide, cacnb4a Peptide
    背景
    CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).

    Alias Symbols: EA5, EJM, CAB4, EIG9, EJM4, EJM6, CACNLB4

    Protein Interaction Partner: CACNA1A,MED31,PTN,REM1,TBL3,CACNA1A,MED31,PTN,TBL3

    Protein Size: 458
    分子量
    50 kDa
    基因ID
    785
    NCBI登录号
    NM_000726, NP_001139270
    UniProt
    A7BJ74
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