Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) Peptide
VHL
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all VHL products
- VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- EDGGEESGAE ESGPEESGPE ELGAEEEMEA GRPRPVLRSV NSREPSQVIF
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of VHL antibody,
Alternative Names: VHL control peptide, VHL antibody Blocking Peptide, Anti-VHL Blocking Peptide, von Hippel-Lindau tumor suppressor Blocking Peptide, HRCA1 Blocking Peptide, RCA1 Blocking Peptide, VHL1 Blocking Peptide
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) peptide
VHL 适用: 人, 大鼠, 小鼠, 犬 宿主: 合成 BP, Imm
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))
- 别名
- HRCA1 Peptide, RCA1 Peptide, VHL1 Peptide, pVHL Peptide, BcDNA:RH61560 Peptide, CG13221 Peptide, DVhl Peptide, Dmel\\CG13221 Peptide, Dvhl Peptide, VHL Peptide, d-VHL Peptide, d-vhl Peptide, dVHL Peptide, dmVHL Peptide, vhl Peptide, rca1 Peptide, vhl1 Peptide, hrca1 Peptide, zgc:158722 Peptide, Vhlh Peptide, von Hippel-Lindau tumor suppressor Peptide, von Hippel-Lindau Peptide, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Peptide, von Hippel-Lindau disease tumor suppressor Peptide, VHL Peptide, Vhl Peptide, vhl Peptide, CpipJ_CPIJ009992 Peptide
- 背景
- Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- 分子量
- 19 kDa
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