A synthetic peptide for use as a blocking control in assays to test for specificity of MELK antibody, Alternative Names: MELK control peptide, MELK antibody Blocking Peptide, Anti-MELK Blocking Peptide, Maternal Embryonic Leucine Zipper Kinase Blocking Peptide, HPK38 Blocking Peptide, KIAA0175 Blocking Peptide
纯化方法
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
The protein MELK phosphorylates ZNF622 and may contribute to its redirection to the nucleus. Also it may be involved in the inhibition of spliceosome assembly during mitosis.