Ubiquitin Specific Peptidase 2 (USP2) (Middle Region) Peptide
USP2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all USP2 products
- USP2 (Ubiquitin Specific Peptidase 2 (USP2))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- FLLDGLHNEV NRVTLRPKSN PENLDHLPDD EKGRQMWRKY LEREDSRIGD
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- USP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- USP2 (Ubiquitin Specific Peptidase 2 (USP2))
- 别名
- UBP41 Peptide, USP9 Peptide, B930035K21Rik Peptide, Ubp41 Peptide, UBP-t Peptide, UBP46 Peptide, ubp52 Peptide, ubp66 Peptide, zgc:92134 Peptide, ubiquitin specific peptidase 2 Peptide, ubiquitin specific peptidase 2a Peptide, USP2 Peptide, Usp2 Peptide, usp2a Peptide
- 背景
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This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: USP9, UBP41
Protein Size: 605 - 基因ID
- 9099
- NCBI登录号
- NM_001243759, NP_001230688
- UniProt
- O75604
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