Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (C-Term) Peptide
UHRF1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all UHRF1 products
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- DDEPGPWTKE GKDRIKKLGL TMQYPEGYLE ALANREREKE NSKREEEEQQ
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-UHRF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- 别名
- ICBP90 Peptide, Np95 Peptide, RNF106 Peptide, hNP95 Peptide, hUHRF1 Peptide, AL022808 Peptide, NP95 Peptide, fb97f09 Peptide, wu:fb97f09 Peptide, zgc:63539 Peptide, UHRF1 Peptide, ubiquitin like with PHD and ring finger domains 1 Peptide, ubiquitin-like, containing PHD and RING finger domains, 1 Peptide, ubiquitin-like with PHD and ring finger domains 1 Peptide, UHRF1 Peptide, Uhrf1 Peptide, uhrf1 Peptide
- 背景
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This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Size: 793 - 分子量
- 90 kDa
- 基因ID
- 29128
- UniProt
- Q96T88
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