PDE6A 抗体
(phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008].
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PDE6A
适用: 人, 小鼠, 大鼠, Hamster, Cow, 犬, 豚鼠, 马, 斑马鱼, Bat
WB
宿主: 兔
Polyclonal
unconjugated
PDE6A
适用: 人, 小鼠, 大鼠
WB, IHC, ELISA, IF, ICC, FACS
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our PDE6A 抗体
: "Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype." in: Human molecular genetics, Vol. 24, Issue 19, pp. 5486-99, (2015) (PubMed).: "Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers." in: PLoS ONE, Vol. 7, Issue 3, pp. e32927, (2012) (PubMed).
: "Gene therapy successfully delays degeneration in a mouse model of PDE6A-linked retinitis pigmentosa (RP 43)." in: Human gene therapy (PubMed).
Aliases for PDE6A 抗体
phosphodiesterase 6A, cGMP-specific, rod, alpha (pde6a) 抗体phosphodiesterase 6A (PDE6A) 抗体
phosphodiesterase 6A (pde6a) 抗体
phosphodiesterase 6A, cGMP-specific, rod, alpha (Pde6a) 抗体
phosphodiesterase 6A (Pde6a) 抗体
CGPR-A 抗体
nmf282 抗体
PDEA 抗体
Pdea 抗体
RP43 抗体
si:bz1d10.3 抗体
si:rp71-1d10.3 抗体
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