PDE6A 抗体 (N-Term)
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北京 101111
Quick Overview for PDE6A 抗体 (N-Term) (ABIN2786520)
抗原
See all PDE6A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PDE6A Antibody - N-terminal region
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序列
- YRTRNGIAEL ATRLFNVHKD AVLEDCLVMP DQEIVFPLDM GIVGHVAHSK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PDE6A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human PDE6A
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anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 11-237) antibody
PDE6A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 656-860) antibodyPDE6A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (N-Term) antibodyPDE6A 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 656-860) antibodyPDE6A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) antibodyPDE6A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 308-336) antibodyPDE6A 适用: 人 WB 宿主: 兔 Polyclonal RB33012 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56111-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
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别名
- PDE6A
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背景
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Background Information: This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
Gene Name: phosphodiesterase 6A
Alternative Symbols: PDEA, RP43, CGPR-A
Protein Name: rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
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分子量
- 85kDa
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基因ID
- 5145
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NCBI登录号
- NP_000431
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UniProt
- P16499
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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