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PDE4A 抗体

(phosphodiesterase 4A, CAMP-Specific (PDE4A))
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
PDE4A 抗体 PDE4A 抗体 PDE4A 抗体 (ABIN1500089)

PDE4A 适用: 人 FACS, IF, IHC, IHC (p), WB 宿主: 小鼠 Monoclonal 5C6 unconjugated

PDE4A 抗体 PDE4A 抗体 PDE4A 抗体 (ABIN2728496)

PDE4A 适用: 人 FACS, IF, WB 宿主: 小鼠 Monoclonal 1E3 unconjugated

PDE4A 抗体 (ABIN2750880)

PDE4A 适用: 人, 小鼠, 大鼠, Elk CM, ICC, IF, IP, IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

PDE4A 抗体 by 适用

Find PDE4A 抗体 for a variety of species such as anti-Human PDE4A, anti-Mouse PDE4A, anti-Rat PDE4A. The species listed below are among those available. Click on a link to go to the corresponding products.

PDE4A 抗体 by 应用范围

Find PDE4A 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDE4A 抗体 by 抗体来源

Find PDE4A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PDE4A 抗体 by 抗原表位

Find PDE4A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDE4A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PDE4A 抗体. Click on a link to go to the corresponding products.

PDE4A 抗体 by 克隆

Find PDE4A 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PDE4A 抗体 by 标记

Find PDE4A 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDE4A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken, Human, Monkey, Mouse, Rat
Application CM, ICC, IF, IP, IHC, ELISA, WB
Validations
  • (13)
Cat. No. ABIN2747099
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN948232
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN518721
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, IHC, WB
Validations
  • (1)
Cat. No. ABIN341175
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), IP, WB
Validations
  • (1)
Cat. No. ABIN1042648
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IHC, IP, WB
Validations
Cat. No. ABIN7117427
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
Cat. No. ABIN7243706
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
Cat. No. ABIN7269302
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC
Validations
Cat. No. ABIN2148617
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC, WB
Validations
Cat. No. ABIN2148621
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC
Validations
Cat. No. ABIN2148618
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF (p), IHC (p), WB
Validations
Cat. No. ABIN1387127
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN5673441
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
Cat. No. ABIN7094514
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
Cat. No. ABIN1539298
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our PDE4A 抗体

Ale-Agha, Goy, Jakobs, Spyridopoulos, Gonnissen, Dyballa-Rukes, Aufenvenne, von Ameln, Zurek, Spannbrucker, Eckermann, Jakob, Gorressen, Abrams, Grandoch, Fischer, Köhrer, Deenen, Unfried, Altschmied et al.: "CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine. ..." in: PLoS biology, Vol. 16, Issue 6, pp. e2004408, (2018) (PubMed).

Lee, Shin, Hong: "The Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells." in: Mediators of inflammation, Vol. 2016, pp. 3745961, (2017) (PubMed).

Avila, Barker, Zhang, McClain, Barve, Gobejishvili: "Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis." in: The Journal of pathology, Vol. 240, Issue 1, pp. 96-107, (2017) (PubMed).

Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Kedia, Ückert, Oelke, Sonnenberg, Sohn, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).

Yougbaré, Boire, Roy, Lugnier, Rouseau: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).

Guo, Lin, Zhao, Zhang, Wei, Wang, Wang: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." in: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).

Zhai, Chang, Wei, Liu, Leblais, Fischmeister, Ji: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).

Wang, Zhang, Liu, Zhao, Zhang, Yuan, An, Li, Wang, Qin, Wilson, ODonnell, Zhang, Li: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." in: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).

Aliases for PDE4A 抗体

phosphodiesterase 4A S homeolog (pde4a.S) 抗体
phosphodiesterase 4A, cAMP-specific (pde4a) 抗体
phosphodiesterase 4A (PDE4A) 抗体
phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) (PDE4A) 抗体
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (LOC100009247) 抗体
phosphodiesterase 4A (Pde4a) 抗体
phosphodiesterase 4A (pde4a) 抗体
phosphodiesterase 4A, cAMP specific (Pde4a) 抗体
phosphodiesterase 4C (PDE4C) 抗体
phosphodiesterase 4A, cAMP-specific (PDE4A) 抗体
D9Ertd60e 抗体
dpde2 抗体
Dpde2 抗体
DPDE2 抗体
pde4 抗体
PDE4 抗体
PDE4A 抗体
Pde4a 抗体
pde46 抗体
PDE46 抗体
PHOSA 抗体
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