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NLRP3 抗体

(NLR Family, Pyrin Domain Containing 3 (NLRP3))
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq, Oct 2008].
NLRP3 抗体  (Pyrin Domain) NLRP3 抗体  (Pyrin Domain) NLRP3 抗体 (Pyrin Domain) (ABIN1169100)

NLRP3 适用: 人, 小鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal Cryo-2 unconjugated

NLRP3 抗体  (AA 15-120) NLRP3 抗体  (AA 15-120) NLRP3 抗体 (AA 15-120) (ABIN1386361)

NLRP3 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC (p), IF (p), FACS, ICC, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

NLRP3 抗体  (AA 671-1033) NLRP3 抗体  (AA 671-1033) NLRP3 抗体 (AA 671-1033) (ABIN7443710)

NLRP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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Find NLRP3 抗体 for a variety of species such as anti-Human NLRP3, anti-Mouse NLRP3, anti-Rat NLRP3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular NLRP3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, IP
Validations
  • (60)
  • (5)
Cat. No. ABIN1169100
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (p), FACS, ICC, IF (cc), IHC (fro)
Validations
  • (11)
  • (15)
Cat. No. ABIN1386361
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7443710
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (8)
Cat. No. ABIN184887
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6144662
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF, FACS, ICC
Validations
  • (7)
Cat. No. ABIN3032021
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7160827
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN5584572
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rat
Application IF (p), FACS, IF (cc)
Validations
  • (1)
Cat. No. ABIN1388260
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN3043571
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7177710
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP, IHC (f)
Validations
  • (1)
Cat. No. ABIN7211585
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN570839
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (4)
Cat. No. ABIN1169101
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856319
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our NLRP3 抗体

Qu, Fan, Qi, Xu, Hu, Chen, Liu, Liu, Si: "Akkermansia muciniphila Alleviates Dextran Sulfate Sodium (DSS)-Induced Acute Colitis by NLRP3 Activation." in: Microbiology spectrum, Vol. 9, Issue 2, pp. e0073021, (2022) (PubMed).

Lv, Liu, Ye, Yang, Duan, Yao, Li, Tang, Chen, Liu, Deng, Wang, Xing, Liang, Xu, Ye: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).

An, Zhang, Cao, Chen, Qin, Yang: "Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway." in: Nutrients, Vol. 12, Issue 5, (2021) (PubMed).

Li, Jiang, Ye, Zhou, Liu, Yang, Hao, Hu: "P2Y14 receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages." in: Cell death & disease, Vol. 11, Issue 5, pp. 394, (2021) (PubMed).

Zhou, Xiao, Zhao, Tan, Long, Yu, He: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).

Wu, Pan, Luo, Shen, Meng, Xiao, Tan, Nie, Tong, Wang: "Roseburia intestinalis‑derived flagellin ameliorates colitis by targeting miR‑223‑3p‑mediated activation of NLRP3 inflammasome and pyroptosis." in: Molecular medicine reports, Vol. 22, Issue 4, pp. 2695-2704, (2021) (PubMed).

Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

Zhu, Tang: "LncRNA Gm14205 induces astrocytic NLRP3 inflammasome activation via inhibiting oxytocin receptor in postpartum depression." in: Bioscience reports, Vol. 40, Issue 8, (2020) (PubMed).

Wong, Lewis, Doherty, Shi, Cashikar, Amelianchik, Tymchuk, Sullivan, Qian, Covey, Petsko, Holtzman, Paul, Luo: "25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner." in: Journal of neuroinflammation, Vol. 17, Issue 1, pp. 192, (2020) (PubMed).

Hoyle, Redondo-Castro, Cook, Tzeng, Allan, Brough, Lemarchand: "Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture." in: Immunology, Vol. 161, Issue 1, pp. 39-52, (2020) (PubMed).

Aliases for NLRP3 抗体

NLR family pyrin domain containing-like (NLRPL) 抗体
NLR family pyrin domain containing 3 (NLRP3) 抗体
NLR family, pyrin domain containing 3 L homeolog (nlrp3.L) 抗体
NLR family, pyrin domain containing 3 (Nlrp3) 抗体
agtavprl 抗体
AGTAVPRL 抗体
AII 抗体
AII/AVP 抗体
avp 抗体
AVP 抗体
C1orf7 抗体
CIAS1 抗体
cias1 抗体
Cias1 抗体
CLR1.1 抗体
FCAS 抗体
FCU 抗体
Mmig1 抗体
MWS 抗体
Nalp3 抗体
nalp3 抗体
NALP3 抗体
pypaf1 抗体
PYPAF1 抗体
Pypaf1 抗体
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