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LKB1 产品

(serine/threonine Kinase 11 (STK11))

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This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

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Featured LKB1 Categories

LKB1 抗体

High quality antibodies with extensive validation data.

LKB1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

LKB1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LKB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
  • (11)
Cat. No. ABIN3022973
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7260193
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (1)
  • (5)
Cat. No. ABIN391350
Quantity 400 μL
Datasheet Datasheet

Recommended LKB1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970117
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959388
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1157394
Quantity 96 tests
Datasheet Datasheet

Recommended LKB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570533
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125040
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1785226
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our LKB1 Products

Rao, Kirschen, Szczurkowska, Di Antonio, Wang, Ge, Shelly: "Repositioning of Somatic Golgi Apparatus Is Essential for the Dendritic Establishment of Adult-Born Hippocampal Neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 3, pp. 631-647, (2019) (PubMed).

Ohtake, Sami, Jiang, Horiuchi, Slattery, Ma, Smith, Selzer, Muramatsu, Li: "Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 102-117, (2019) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Zhang, Geng, Liu, Li, Gao, Liu, Fang, Chang: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).

Yan, Du, Li, Chen, Yan, Chen, Hu, Chang: "CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo." in: Urologic oncology, Vol. 36, Issue 6, pp. 312.e1-312.e8, (2018) (PubMed).

Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

Wang, Zhao, Yu, Feng, Zhang, Kou, Chu, Cui, Li, Zhang, Shen, Min: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." in: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).

Zhao, Zhang, Liu, Zhang, Hao, Li, Chen, Shen, Tang, Min, Meng, Wang, Yi, Zhang: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." in: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).

Tang, Li, Wang, Threadgill, Xiao, Mou, Song, Kuang, Yang, Yang, Gao, Wang, Meng: "ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma." in: American journal of cancer research, Vol. 5, Issue 2, pp. 498-513, (2015) (PubMed).

Dahmani, Just, Delay, Canal, Finzi, Prip-Buus, Lambert, Sujobert, Buchet-Poyau, Miller, Cavard, Marmier, Terris, Billaud, Perret: "A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties." in: Oncogene, Vol. 34, Issue 18, pp. 2337-46, (2015) (PubMed).

Synonyms and alternative names related to LKB1

serine/threonine kinase 11 (STK11), serine/threonine kinase 11 (stk11), polarization-related protein LKB1 (LOC662493), serine/threonine kinase 11 (Stk11), serine/threonine kinase 11 L homeolog (stk11.L), AA408040, hLKB1, LKB1, Lkb1, mLKB1, Par-4, pjs, PJS, R75140, Stk11, wu:fj61a05, XEEK1, xeek1, zgc:110180

Protein level used designations for LKB1

  • serine/threonine protein kinase 11
  • serine/threonine kinase 11 (Peutz-Jeghers syndrome)
  • GLEAN_12166
  • Serine/threonine-protein kinase 11
  • serine/threonine-protein kinase STK11
  • serine/threonine kinase 11
  • serine/threonine-protein kinase 11-like
  • liver kinase B1
  • polarization-related protein LKB1
  • renal carcinoma antigen NY-REN-19
  • serine/threonine-protein kinase 11
  • serine/threonine-protein kinase LKB1
  • LKB1 short isoform
  • liver kinase B1 homolog
  • lkb1
  • egg and embryo kinase 1
  • serine/threonine-protein kinase XEEK1
  • serine/threonine-protein kinase stk11
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