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LKB1 抗体 (N-Term)

Name: LKB1 抗体 (N-Term)
SKU: ABIN391350
Availability: OutOfStock

STK11 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB3547 unconjugated

Western blot analysis of STK11 (arrow) using rabbit polyclonal STK11 Antibody (ABIN391350 and ABIN2841371). (LKB1 抗体 (N-Term))

STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control cell (left histogram). (LKB1 抗体 (N-Term))

FACS

Confocal immunofluorescent analysis of STK11 (LKB1) Antibody (N-term I29) (ABIN391350 and ABIN2841371) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (LKB1 抗体 (N-Term))

STK11 Antibody (I29) (ABIN391350 and ABIN2841371) western blot analysis in T47D cell line lysates (35 μg/lane). (LKB1 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (LKB1 抗体 (N-Term))

IHC (p)

5 images

(1 reference)

产品编号 ABIN391350

发货至: 中国

Datasheet as PDF

抗原 See all LKB1 (STK11) 抗体

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
抗原表位
27

23

20

19

15

15

8

7

7

7

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 14-44, N-Term
适用
172

115

63

16

15

7

6

5

4

3

3

3

2

1

1
人
宿主
177

9
兔
Compatible Secondaries
克隆类型
180

6
多克隆
标记
80

11

9

9

7

7

7

7

7

7

5

5

5

5

5

4

4

2
This LKB1 antibody is un-conjugated
应用范围
140

74

65

65

33

27

20

15

6

4

3

2

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

预测反应

C, M, Rat, X

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).

克隆位点

RB3547

亚型

Ig Fraction

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anti-serine/threonine Kinase 11 (STK11) (AA 134-433) antibody
STK11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) antibody
STK11 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 14-44) antibody
STK11 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (pSer428) antibody
STK11 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 19-48) antibody
STK11 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Tyr1313) antibody
STK11 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (AA 1-433) antibody
STK11 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (Internal Region) antibody
STK11 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (pThr189) antibody
STK11 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-serine/threonine Kinase 11 (STK11) (N-Term) antibody
STK11 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

有效期

6 months
Sohn, Jang, Campan, Weisenberger, Dickhout, Wang, Cho, Yates, Lucock, Chiang, Austin, Choi, Laird, Kim et al.: "The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer ..." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 1999-2005, (2009) (PubMed).
抗原

LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

别名

STK11 (LKB1) (STK11 产品)

别名

pjs antibody, LKB1 antibody, XEEK1 antibody, Stk11 antibody, PJS antibody, hLKB1 antibody, AA408040 antibody, Lkb1 antibody, Par-4 antibody, R75140 antibody, mLKB1 antibody, wu:fj61a05 antibody, zgc:110180 antibody, xeek1 antibody, serine/threonine kinase 11 antibody, polarization-related protein LKB1 antibody, serine/threonine kinase 11 L homeolog antibody, STK11 antibody, stk11 antibody, LOC662493 antibody, Stk11 antibody, stk11.L antibody

背景

STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

分子量

48636

NCBI登录号

NP_000446

UniProt

Q15831

途径

AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect