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LKB1 抗体

STK11 适用: 人, 小鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4H12 unconjugated
产品编号 ABIN969424
发货至: 中国
  • 抗原 See all LKB1 (STK11) 抗体
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    适用
    • 172
    • 114
    • 63
    • 16
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 猴
    宿主
    • 178
    • 8
    小鼠
    克隆类型
    • 181
    • 5
    单克隆
    标记
    • 80
    • 11
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
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    • 4
    • 2
    This LKB1 antibody is un-conjugated
    应用范围
    • 140
    • 73
    • 65
    • 65
    • 33
    • 28
    • 21
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human STK11 expressed in E. coli. ,
    克隆位点
    4H12
    亚型
    IgG1
    Top Product
    Discover our top product STK11 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Al-Nashash, Fatoo, Mirza, Ahmed, Agrawal, Thakor, All: "Spinal cord injury detection and monitoring using spectral coherence." in: IEEE transactions on bio-medical engineering, Vol. 56, Issue 8, pp. 1971-9, (2009) (PubMed).

    Shaw: "Tumor suppression by LKB1: SIK-ness prevents metastasis." in: Science signaling, Vol. 2, Issue 86, pp. pe55, (2009) (PubMed).

    Cheng, Liu, Wang, Zou, Santiago, Garbitt, Gjoerup, Iglehart, Miron, Richardson, Hahn, Zhao: "SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis." in: Science signaling, Vol. 2, Issue 80, pp. ra35, (2009) (PubMed).

  • 抗原
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    别名
    STK11 (STK11 产品)
    别名
    pjs antibody, LKB1 antibody, XEEK1 antibody, Stk11 antibody, PJS antibody, hLKB1 antibody, AA408040 antibody, Lkb1 antibody, Par-4 antibody, R75140 antibody, mLKB1 antibody, wu:fj61a05 antibody, zgc:110180 antibody, xeek1 antibody, serine/threonine kinase 11 antibody, polarization-related protein LKB1 antibody, serine/threonine kinase 11 L homeolog antibody, STK11 antibody, stk11 antibody, LOC662493 antibody, Stk11 antibody, stk11.L antibody
    背景

    Description: Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase 11,with two alternatively spliced isoforms,expressed in all tissues,strongly homolog of Xenopus early embryonic kinase 1 (XEEK1),tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis,mutated in sporadic testicular cancer,malignant melanomas and laryngeal tumors,playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity: Ubiquitously expressed. Strongest expression in testis and fetal liver.

    Aliases: PJS, LKB1, STK11

    分子量
    54 kDa
    基因ID
    6794
    HGNC
    6794
    途径
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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