LLGL2 产品
(Lethal Giant Larvae Homolog 2 (LLGL2))
Categories
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured LLGL2 Categories
Recommended LLGL2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (6)
- (4)
Cat. No.
ABIN561680
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (3)
Cat. No.
ABIN7264313
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN948088
Quantity
100 μL
Datasheet
Datasheet
Recommended LLGL2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309482
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309484
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3093413
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our LLGL2 Products
: "A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia." in: The Journal of cell biology, Vol. 211, Issue 2, pp. 273-86, (2015) (PubMed).: "Distinguishing Barrett gastric foveolar dysplasia from reactive cardiac mucosa in gastroesophageal reflux disease." in: Human pathology, Vol. 44, Issue 6, pp. 1146-53, (2013) (PubMed).
: "Loss of Scribble causes cell competition in mammalian cells." in: Journal of cell science, Vol. 125, Issue Pt 1, pp. 59-66, (2012) (PubMed).
: "Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation." in: PLoS ONE, Vol. 7, Issue 10, pp. e47734, (2012) (PubMed).
: "ASPP2 regulates epithelial cell polarity through the PAR complex." in: Current biology : CB, Vol. 20, Issue 15, pp. 1408-14, (2010) (PubMed).
: "Involvement of Lgl and Mahjong/VprBP in cell competition." in: PLoS biology, Vol. 8, Issue 7, pp. e1000422, (2010) (PubMed).
: "Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6761-5, (2005) (PubMed).
: "Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico." in: International journal of oncology, Vol. 24, Issue 3, pp. 737-42, (2004) (PubMed).
Synonyms and alternative names related to LLGL2
LLGL2, scribble cell polarity complex component L homeolog (llgl2.L), LLGL2, scribble cell polarity complex component (llgl2), lethal giant larvae homolog 2 (Drosophila) (llgl2), LLGL2, scribble cell polarity complex component (LLGL2), lethal giant larvae homolog 2 (Drosophila) (Llgl2), LLGL2, scribble cell polarity complex component (Llgl2), 9130006H11Rik, cb521, hgl, HGL, lgl-2, Lgl-2, lgl2, LGL2, llglh2, Llglh2, RGD1560307, sb:cb521, wu:fc06g08, wu:fl37c09, zgc:55895Protein level used designations for LLGL2
- lethal giant larvae 2
- lethal giant larva 2
- lethal(2) giant larvae protein homolog 2
- pen
- penner
- protein penner
- human giant larvae homolog
- lethal giant larvae-like protein 2
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