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IL-6 ELISA 试剂盒

This Colorimetric ELISA kit is designed for the quantitative measurement of 人 IL-6.
产品编号 ABIN577085
发货至: 中国
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Quick Overview for IL-6 ELISA 试剂盒 (ABIN577085)

抗原

See all IL-6 (IL6) ELISA试剂盒
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    This IL-6 enzyme linked immunosorbent assay (ELISA) applies a technique called a quantitative sandwich immunoassay. The microtiter plate provided in this kit has been pre-coated with a monoclonal antibody specific to IL-6. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody preparation specific for IL-6 and incubated. IL-6 if present, will bind and become immobilized by the antibody pre-coated on the wells and then be

    Analytical Method

    Quantitative

    灵敏度

    The minimum detectable dose of IL-6 was determined by adding two standard deviations to the mean optical density value of the zero standard replicates and calculating the corresponding concentration from the standard curve. The minimum detectable dose using a standard curve generated with Calibrator Diluent I is 2.0 pg/mL and using Calibrator Diluent II is 1.75 pg/mL.

    组件

    Standards: 1 set/2 vials
  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存液

    Without preservative
  • 抗原 See all IL-6 (IL6) ELISA试剂盒

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    Interleukin-6 (IL-6)

    背景

    Hepatitis B is an infection of the liver caused by the hepatitis B virus. Approximately 5-1% of adults and 9% of babies who are infected with HBV will go on to carry the virus for the rest of their lives. These people will pass the virus onto others. HBV is excreted in body fluids such as semen, saliva, blood and urine in persons with acute or chronic infection. The route of transmission can include homosexual or heterosexual activity, blood-borne exposure (needles, transfusion), mother-infant, close personal contact and even by consuming contaminated food or water. Thus, Hepatitis B has become a major public health concern. When HBV invades the body it causes liver damage through induction of auto-immunity. Liver cell injury results from cytotoxic T cell activity rather than viral cytotoxic activity. The principle screening test for detecting current (acute or chronic) HBV infection is the identification of HBsAg, an envelope lipoprotein. This is the first immunological marker, to appear in a patient's serum and exist in high quantities in the blood. Patients who are HBsAg positive develop chronic persistent hepatitis (CPH) and chronic active hepatitis (CAH). Patients with CPH usually remain in good health but those with CAH have progressive liver damage with the outcome being portal fibrosis, cirrhosis, or hepatocellular carcinoma. Screening for HBsAg is recommended for all donors, pregnant women and those individuals who at high risk. Presence of this marker is conclusive proof of HBV infection. YBL offers an immunoassay that can measure HBsAg through antigen-antibody interactions

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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