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- 抗原 See all DR3/LARD (TNFRSF25) ELISA试剂盒
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- 抗原表位
- AA 25-201
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TNFRSF25/DR3
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: Q25-F201
- 交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
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Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) ELISA Kit
TNFRSF25 适用: 人 Colorimetric Sandwich ELISA 0.24 ng/mL - 15 ng/mL Plasma, Serum, Tissue Homogenate
Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) ELISA KitTNFRSF25 适用: 小鼠 AA 31-199 Colorimetric Sandwich ELISA
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all DR3/LARD (TNFRSF25) ELISA试剂盒
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- 别名
- TNFRSF25 (TNFRSF25 产品)
- 别名
- APO-3 ELISA Kit, DDR3 ELISA Kit, DR3 ELISA Kit, LARD ELISA Kit, TNFRSF12 ELISA Kit, TR3 ELISA Kit, TRAMP ELISA Kit, WSL-1 ELISA Kit, WSL-LR ELISA Kit, Tnfrsf12 ELISA Kit, Wsl ELISA Kit, TNFRSF25 ELISA Kit, TNF receptor superfamily member 25 ELISA Kit, tumor necrosis factor receptor superfamily, member 25 ELISA Kit, TNFRSF25 ELISA Kit, Tnfrsf25 ELISA Kit
- 背景
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Protein Function: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Background: Death receptor 3 (DR3), also known as tumor necrosis factor receptor superfamily member 25 (TNFRSF25), is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
Synonyms: Tumor necrosis factor receptor superfamily member 25,Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,LARD,Protein WSL,Protein WSL-1,TNFRSF25,APO3, DDR3, DR3, TNFRSF12, WSL, WSL1,UNQ455/PRO779,
Full Gene Name: Tumor necrosis factor receptor superfamily member 25
Cellular Localisation: Isoform 1: Cell membrane, Single-pass type I membrane protein. - UniProt
- Q93038
- 途径
- Apoptosis
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